Name: Oct-3/4 Antibody (240408) [Unconjugated]
Brand: Novus Biologicals
SKU: MAB1759
Price: 469 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	Hu, MuSpecies Glossary
Applications	WB, CyTOF-ready, Flow, ICC/IF
Clone	240408
Clonality	Monoclonal
Host	Rat
Conjugate	Unconjugated
Concentration	LYOPH

Catalog# & Conjugate	Size	Price
Alexa Fluor 350 IC1759U-100UG

Alexa Fluor 405 IC1759V-100UG

Alexa Fluor 488 IC1759G-100UG

Alexa Fluor 594 IC1759T-100UG

Alexa Fluor 647 IC1759R-100UG

Alexa Fluor 700 IC1759N-100UG

Alexa Fluor 750 IC1759S-100UG

Allophycocyanin IC1759A-100

Allophycocyanin IC1759A-025

Fluorescein IC1759F-100

Fluorescein IC1759F-025

Phycoerythrin IC1759P-100

Phycoerythrin IC1759P-025

Catalog# & Formulation	Size	Price
Carrier Free MAB1759-SP

Carrier Free IC1759A-100

Carrier Free IC1759A-025

Carrier Free IC1759F-100

Carrier Free IC1759F-025

Carrier Free IC1759P-100

Carrier Free IC1759P-025

Carrier Free IC1759V-100UG

Carrier Free IC1759U-100UG

Carrier Free IC1759T-100UG

Carrier Free IC1759S-100UG

Carrier Free IC1759R-100UG

Carrier Free IC1759N-100UG

Carrier Free IC1759G-100UG

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	IC1759U-100UG
Alexa Fluor 405	IC1759V-100UG
Alexa Fluor 488	IC1759G-100UG
Alexa Fluor 594	IC1759T-100UG
Alexa Fluor 647	IC1759R-100UG
Alexa Fluor 700	IC1759N-100UG
Alexa Fluor 750	IC1759S-100UG
Allophycocyanin	IC1759A-100
Allophycocyanin	IC1759A-025
Fluorescein	IC1759F-100
Fluorescein	IC1759F-025
Phycoerythrin	IC1759P-100
Phycoerythrin	IC1759P-025

Oct-3/4 Antibody (240408) [Unconjugated]

Species Glossary

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Oct-3/4 Antibody (240408) [Unconjugated] Summary

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Notes

Alternate Names for Oct-3/4 Antibody (240408) [Unconjugated]

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Publications for Oct-3/4 Antibody (MAB1759)(47)

Reviews for Oct-3/4 Antibody (MAB1759) (0)

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Secondary Antibodies

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Bioinformatics

Specificity	Detects human Oct-3/4 in Western blots and detects mouse Oct-3/4 in flow cytometry.
Source	N/A
Isotype	IgG2b
Clonality	Monoclonal
Host	Rat
Gene	POU5F1
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Concentration	LYOPH
Reconstitution Instructions	Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Publications using MAB1759	Applications	Species
Rakotomamonjy, J;Rylaarsdam, L;Fares-Taie, L;McDermott, S;Davies, D;Yang, G;Fagbemi, F;Epstein, M;Fairbanks-Santana, M;Rozet, JM;Guemez-Gamboa, A; PCDH12 loss results in premature neuronal differentiation and impeded migration in a cortical organoid model Cell reports 2023-07-20 [PMID: 37480564] (ICC, Human)	ICC	Human
X Wang, J Sun, C Fu, C Liu Generation of a PPP1CA knockout human pluripotent stem cell line via CRISPR/Cas9 Stem Cell Research, 2023-03-21;69(0):103077. 2023-03-21 [PMID: 36965407] (Flow Cytometry, ICC, Human)	Flow Cytometry, ICC	Human
T Ding, Z Gao, H Liu, Y Li, S Liu, L Jian Establishment of a PPP2CA homozygous knockout human embryonic stem cell line via CRISPR/Cas9 system Stem Cell Research, 2023-01-16;67(0):103029. 2023-01-16 [PMID: 36724553] (Flow Cytometry, Human)	Flow Cytometry	Human
M Zhou, P Huang, R Bai, X Liu Generation of a homozygous TAZ knockout hESCs line by CRISPR/Cas9 system Stem Cell Research, 2022-09-20;64(0):102923. 2022-09-20 [PMID: 36219982] (ICC, Human)	ICC	Human
Julie Bejoy, Justin M. Farry, Jennifer L. Peek, Mariana C. Cabatu, Felisha M. Williams, Richard C. Welch et al. Podocytes derived from human induced pluripotent stem cells: characterization, comparison, and modeling of diabetic kidney disease Stem Cell Research & Therapy 12/1/2022 [PMID: 35883199]
S Farahi, S Hosseini, H Ghanbarian, SM Hashemi, M Salehi, S Hosseini The Use of Trichostatin A during Pluripotent Stem Cell Generation Does Not Affect MHC Expression Level Stem Cells International, 2022-02-15;2022(0):9346767. 2022-02-15 [PMID: 35371264] (ICC/IF, Mouse)	ICC/IF	Mouse
Miki Nishio, Takuya Matsuura, Shunya Hibi, Shiomi Ohta, Chio Oka, Noriaki Sasai et al. Heterozygous loss of Zbtb38 leads to early embryonic lethality via the suppression of Nanog and Sox2 expression Cell Proliferation 4/1/2022 [PMID: 35297517]
K Kwa?niak, J Czarnik-Kw, K Malysheva, K Pogoda, O Korchynsky, P Rybojad, B Karczmarek, J Tabarkiewi LncCDH5-3:3 Regulates Apoptosis, Proliferation, and Aggressiveness in Human Lung Cancer Cells Cells, 2022-01-23;11(3):. 2022-01-23 [PMID: 35159188] (Western Blot, Human)	Western Blot	Human
SK Hota, KS Rao, AP Blair, A Khalilimey, KM Hu, R Thomas, K So, V Kameswaran, J Xu, BJ Polacco, RV Desai, N Chatterjee, A Hsu, JM Muncie, AM Blotnick, SAB Winchester, LS Weinberger, R Hüttenhain, IS Kathiriya, NJ Krogan, JJ Saucerman, BG Bruneau Brahma safeguards canalization of cardiac mesoderm differentiation Nature, 2022-01-26;602(7895):129-134. 2022-01-26 [PMID: 35082446] (ICC, Mouse)	ICC	Mouse
S Zhang, T Guo, Y Song, M Jiang, Y Jiang, T Dong, S Zhang, H Wang, X Hou Generation of a homozygous S100A1 knockout human embryonic stem cell line (WAe009-A-73) by the CRISPR/Cas9 editing system Stem Cell Research, 2021-12-20;59(0):102631. 2021-12-20 [PMID: 34953326] (Flow Cytometry, ICC, Human)	Flow Cytometry, ICC	Human
Julie Bejoy, Eddie Spencer Qian, Lauren Elizabeth Woodard Accelerated protocol for the differentiation of podocytes from human pluripotent stem cells STAR Protocols 12/1/2021 [PMID: 34746862]
S Ma, Q Xu, R Bai, T Dong, Z Peng, X Liu Generation of a TPM1 homozygous knockout embryonic stem cell line by CRISPR/Cas9 editing Stem Cell Research, 2021-07-19;55(0):102470. 2021-07-19 [PMID: 34352617] (ICC, Human)	ICC	Human
X Liu, S Zhang, Y Chang, F Wu, R Bai Establishment of a KCNQ1 homozygous knockout human embryonic stem cell line by episomal vector-based CRISPR/Cas9 system Stem Cell Research, 2021-07-22;55(0):102467. 2021-07-22 [PMID: 34343827] (Flow Cytometry, ICC, Human)	Flow Cytometry, ICC	Human
W Wang, R Bai, X Song Generating dHAND homozygous knockout human embryonic stem cell line (WAe009-A-59) by episomal vector-based CRISPR/Cas9 system Stem Cell Research, 2021-07-20;55(0):102471. 2021-07-20 [PMID: 34332328] (Flow Cytometry, ICC, Human)	Flow Cytometry, ICC	Human
A Getachew, Z Yang, X Huang, F Wu, YY Liu, C Yan, F Yang, Y Li Generation of a TLR2 homozygous knockout human embryonic stem cell line WAe001-A-64 using CRISPR/Cas9 editing Stem Cell Research, 2021-05-21;54(0):102401. 2021-05-21 [PMID: 34058685] (Flow Cytometry, Human)	Flow Cytometry	Human
T Zhao, R Bai, F Wu, WJ Lu, J Zhang Generation of a TBX5 homozygous knockout embryonic stem cell line (WAe009-A-45) by CRISPR/Cas9 genome editing Stem Cell Research, 2021-01-06;51(0):102156. 2021-01-06 [PMID: 33497883] (Flow Cytometry, ICC, Human)	Flow Cytometry, ICC	Human
L Andreasson, H Evenbratt, R Mobini, S Simonsson Differentiation of induced pluripotent stem cells into definitive endoderm on Activin A-functionalized gradient surfaces J Biotechnol, 2020-11-02;0(0):. 2020-11-02 [PMID: 33147515] (Bioassay, ICC, Human)	Bioassay, ICC	Human
F Wu, X Li, R Bai, Y Li, J Gao, F Lan Generation of a Junctophilin-2 homozygous knockout human embryonic stem cell line (WAe009-A-36) by an episomal vector-based CRISPR/Cas9 system Stem Cell Res, 2020-08-03;48(0):101930. 2020-08-03 [PMID: 32777767] (ICC, Human)	ICC	Human
L Wei, J Zhang, D Chen, L Feng, C Wu, R Wang, X Li Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi005-A) from a Wilson's disease patient harboring a homozygous Pro992Leu mutation in ATP7B gene Stem Cell Res, 2020-07-15;47(0):101909. 2020-07-15 [PMID: 32745714] (ICC, Human)	ICC	Human
L Wei, J Zhang, D Chen, L Feng, C Wu, R Wang, X Li Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi002-A) from a patient with spinocerebellar ataxia type 3 Stem Cell Res, 2020-06-29;47(0):101898. 2020-06-29 [PMID: 32650241] (ICC, Human)	ICC	Human
Collins D, Hapke J, Aravalli R, Steer C In vitro Differentiation of TERT-Transfected Multi-Lineage Progenitor Cells (MLPC) into Immortalized Hepatocyte-Like Cells HMER 6/1/2020 [PMID: 32607015]
G Kaufman, NM Kiburi, D Skrtic The self-renewal dental pulp stem cell microtissues challenged by a toxic dental monomer Biosci. Rep., 2020-06-26;40(6):. 2020-06-26 [PMID: 32495822] (ICC, Human)	ICC	Human
J Zhang, L Wei, R Wang, X Li, Z Liu Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi001-A) from a healthy male individual Stem Cell Res, 2020-04-24;45(0):101809. 2020-04-24 [PMID: 32361313] (ICC, Human)	ICC	Human
J Zhang, L Wei, D Chen, L Feng, C Wu, R Wang, X Li, H Liu Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi004-A) from a Wilson's disease patient harboring a homozygous Pro992Leu mutation in ATP7B gene Stem Cell Res, 2020-02-20;44(0):101741. 2020-02-20 [PMID: 32113134] (ICC, Human)	ICC	Human
X Guo, Y Tang, P Zhang, S Li, Y Chen, B Qian, H Shen, N Zhao Effect of ectopic high expression of transcription factor OCT4 on the "stemness" characteristics of human bone marrow-derived mesenchymal stromal cells Stem Cell Res Ther, 2019-06-03;10(1):160. 2019-06-03 [PMID: 31159871] (ICC, Human)	ICC	Human
Katsura Y, Ohara T, Noma K et al. A Novel Combination Cancer Therapy with Iron Chelator Targeting Cancer Stem Cells via Suppressing Stemness Cancers (Basel) 2/3/2019 [PMID: 30717462]
N Ito, K Katoh, H Kushige, Y Saito, T Umemoto, Y Matsuzaki, H Kiyonari, D Kobayashi, M Soga, T Era, N Araki, Y Furuta, T Suda, Y Kida, K Ohta Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency Sci Rep, 2018-01-26;8(1):1634. 1/26/2018 [PMID: 29374279]
G Xu, D Guo, F Wu, N Abbas, K Lai, F Yuan, K You, Y Liu, Y Zhuang, Y Wu, Y Xu, Y Chen, F Yang, T Pan, YX Li Generation of a GDE heterozygous mutation human embryonic stem cell line WAe001-A-14 by CRISPR/Cas9 editing Stem Cell Res, 2017-12-13;27(0):38-41. 2017-12-13 [PMID: 29310060] (ICC, Human)	ICC	Human
F Wu, G Gao, T Pan, Z Yang, G Xu, N Abbas, Y Liu, Y Chen, S Tan, K You, X Ke, Y Zhuang, X Lin, F Yang, YX Li Generation of a SMO homozygous knockout human embryonic stem cell line WAe001-A-16 by CRISPR/Cas9 editing Stem Cell Res, 2017-12-05;27(0):5-9. 2017-12-05 [PMID: 29278761] (ICC, Human)	ICC	Human
Takayuki Ninomiya, Toshiaki Ohara, Kazuhiro Noma, Yuki Katsura, Ryoichi Katsube, Hajime Kashima et al. Iron depletion is a novel therapeutic strategy to target cancer stem cells Oncotarget 11/17/2017 [PMID: 29228699]
Y Xu, Y Wu, D Guo, G Gao, K Lai, F Yang, K Wang, H Wu, L Lai, J Li, K Xu, YX Li Generation of an ASGR1 homozygous mutant human embryonic stem cell line WAe001-A-6 using CRISPR/Cas9 Stem Cell Res, 2017-05-19;22(0):29-32. 2017-05-19 [PMID: 28952928] (ICC, Human)	ICC	Human
G Kaufman, D Skrtic Spatial development of gingival fibroblasts and dental pulp cells: Effect of extracellular matrix Tissue Cell, 2017-04-10;0(0):. 2017-04-10 [PMID: 28457531] (ICC, Mouse)	ICC	Mouse
P Wang, C Lan, S Xiong, X Zhao, Y Shan, R Hu, W Wan, S Yu, B Liao, G Li, J Wang, D Zou, B Chen, H Feng, N Wu HIF1? regulates single differentiated glioma cell dedifferentiation to stem-like cell phenotypes with high tumorigenic potential under hypoxia Oncotarget, 2017-04-25;8(17):28074-28092. 2017-04-25 [PMID: 28427209] (ICC, Western Blot, Human)	ICC, Western Blot	Human
Tomomi Kotoku, Koji Kosaka, Miki Nishio, Yasumasa Ishida, Masashi Kawaichi, Eishou Matsuda CIBZ Regulates Mesodermal and Cardiac Differentiation of by Suppressing T and Mesp1 Expression in Mouse Embryonic Stem Cells Scientific Reports 9/23/2016 [PMID: 27659197]
Zangiacomi Vincent, Kenichi Urakami, Koji Maruyama, Ken Yamaguchi, Masatoshi Kusuhara CD133-positive cancer stem cells from colo205 human colon adenocarcinoma cell line show resistance to chemotherapy and display a specific metabolomic profile Genes & Cancer 7/27/2014 [PMID: 25221643]
Hagiwara , Kunie, Obayashi , Takeshi, Sakayori , Nobuyuki, Yamanishi , Emiko, Hayashi , Ryuhei, Osumi , Noriko, Nakazawa , Toru, Nishida , Kohji Molecular and cellular features of murine craniofacial and trunk neural crest cells as stem cell-like cells. PLoS ONE, 2014-01-20;9(1):e84072. 2014-01-20 [PMID: 24465393] (ICC, Mouse)	ICC	Mouse
Cortes-Dericks , Lourdes, Yazd , Ehsan Fa, Mowla , Seyed J, Schmid , Ralph A, Karoubi , Golnaz Suppression of OCT4B enhances sensitivity of lung adenocarcinoma A549 cells to cisplatin via increased apoptosis. Anticancer Res, 2013-12-01;33(12):5365-73. 2013-12-01 [PMID: 24324071] (Western Blot, Human)	Western Blot	Human
Pekkanen-Mattila M, Ojala M, Kerkela E, Rajala K, Skottman H, Aalto-Setala K The effect of human and mouse fibroblast feeder cells on cardiac differentiation of human pluripotent stem cells. Stem Cells Int, 2012-01-19;2012(0):875059. 2012-01-19 [PMID: 22315618] (ICC, Human)	ICC	Human
Kambal A, Mitchell G, Cary W, Gruenloh W, Jung Y, Kalomoiris S, Nacey C, McGee J, Lindsey M, Fury B, Bauer G, Nolta JA, Anderson JS Generation of HIV-1 resistant and functional macrophages from hematopoietic stem cell-derived induced pluripotent stem cells. Mol. Ther., 2010-11-30;19(3):584-93. 2010-11-30 [PMID: 21119622] (ICC, Human)	ICC	Human
Klim JR, Li L, Wrighton PJ A defined glycosaminoglycan-binding substratum for human pluripotent stem cells. Nat. Methods, 2010-11-14;7(12):989-94. 2010-11-14 [PMID: 21076418] (ICC, Human)	ICC	Human
Angel M, Yanik MF Innate immune suppression enables frequent transfection with RNA encoding reprogramming proteins. PLoS ONE, 2010-07-23;5(7):e11756. 2010-07-23 [PMID: 20668695] (ICC, Human)	ICC	Human
Semenov O, Koestenbauer S, Riegel M, Zech N, Zimmermann R, Zisch A, Malek A Multipotent mesenchymal stem cells from human placenta: critical parameters for isolation and maintenance of stemness after isolation. Am J Obstet Gynecol, 2009-12-24;202(2):193.e1-193.e1. 2009-12-24 [PMID: 20035913] (IHC, Human)	IHC	Human
Ware CB, Wang L, Mecham BH, Shen L, Nelson AM, Bar M, Lamba DA, Dauphin DS, Buckingham B, Askari B, Lim R, Tewari M, Gartler SM, Issa JP, Pavlidis P, Duan Z, Blau CA Histone deacetylase inhibition elicits an evolutionarily conserved self-renewal program in embryonic stem cells. Cell Stem Cell, 2009-04-03;4(4):359-69. 2009-04-03 [PMID: 19341625] (ICC, Mouse)	ICC	Mouse
Hu T, Liu S, Breiter DR, Wang F, Tang Y, Sun S Octamer 4 small interfering RNA results in cancer stem cell-like cell apoptosis. Cancer Res., 2008-08-15;68(16):6533-40. 2008-08-15 [PMID: 18701476] (IHC-Fr, Mouse)	IHC-Fr	Mouse
Cordey M, Limacher M, Kobel S, Taylor V, Lutolf MP Enhancing the reliability and throughput of neurosphere culture on hydrogel microwell arrays. Stem Cells, 2008-07-31;26(10):2586-94. 2008-07-31 [PMID: 18669905] (ICC, Mouse)	ICC	Mouse
Hohenstein KA, Pyle AD, Chern JY, Lock LF, Donovan PJ Nucleofection mediates high-efficiency stable gene knockdown and transgene expression in human embryonic stem cells. Stem Cells, 2008-03-06;26(6):1436-43. 2008-03-06 [PMID: 18323409] (ICC, Human)	ICC	Human
Rajesh</LastName><ForeNam D</Initial, Rajesh D, Chinnasamy N, Mitalipov SM, Wolf DP, Slukvin I, Thomson JA, Shaaban AF Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells. Stem Cells, 2007-02-01;25(2):490-9. 2007-02-01 [PMID: 17284653] (Flow Cytometry, Human, Primate - Macaca mulatta (Rhesus Macaque))	Flow Cytometry	Human, Primate - Macaca mulatta (Rhesus Macaque)
Show All 47 Publications. Collapse Publications.

Gene Symbol	POU5F1
Uniprot	Q01860()