Does this NLRP3/NALP3 antibody come in lyophilized form?

Yes, we carry this NLRP2 antibody in lyophilized format.

What is the immunogen sequence of this NLRP3/NALP3 antibodies antibody?

An E. coli derived sequence corresponding to Met1 - Arg153 of mouse NLRP3/NALP3.

Are the NLRP3/NALP3 antibodies validated in Simple Western?

Yes, we offer a NLRP3/NALP3 antibody that have been tested in Simple Western: NBP2-03948.

Does NLRP3/NALP3 antibodies come in lyophilized form?

Yes, we carry 3 NLRP2 antibodies in lyophilized format: AF6789, AF7010, MAB6789, MAB7578.

What is the theoretical molecular weight for NLRP3/NALP3 antibodies?

The TMW of NLRP3/NALP3 antibodies is approximately 118 kDa.

NLRP3/NALP3 Antibody (768319) [Unconjugated] (MAB7578): Novus Biologicals

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	Hu, MuSpecies Glossary
Applications	WB, IHC, CyTOF-ready, Flow, ICC/IF
Clone	768319
Clonality	Monoclonal
Host	Rat
Conjugate	Unconjugated
Concentration	LYOPH

Catalog# & Conjugate	Size	Price
Alexa Fluor 350 IC7578U-100UG

Alexa Fluor 488 IC7578G

Alexa Fluor 532 FAB7578X

Alexa Fluor 594 IC7578T-100UG

Alexa Fluor 647 IC7578R-100UG

Alexa Fluor 700 IC7578N

Alexa Fluor 750 IC7578S-100UG

Allophycocyanin IC7578A

Biotin FAB7578B

CoraFluor 1 FAB7578CL1

DyLight 350 FAB7578D

DyLight 405 FAB7578E

DyLight 488 FAB7578K

DyLight 550 FAB7578L

DyLight 594 FAB7578M

DyLight 650 FAB7578W

DyLight 680 FAB7578Y

DyLight 755 FAB7578Z

FITC FAB7578F

HRP FAB7578H

Janelia Fluor 525 FAB7578JF525

Janelia Fluor 549 FAB7578I

Janelia Fluor 646 FAB7578J

Janelia Fluor 669 FAB7578JF669

Phycoerythrin IC7578P

mFluor Violet 450 SE FAB7578MFV450

mFluor Violet 500 SE FAB7578MFV500

mFluor Violet 610 SE FAB7578MFV610

Catalog# & Formulation	Size	Price
Carrier Free IC7578P

Carrier Free IC7578A

Carrier Free IC7578G

Carrier Free IC7578N

Carrier Free MAB7578-SP

Carrier Free IC7578U-100UG

Carrier Free IC7578T-100UG

Carrier Free IC7578S-100UG

Carrier Free IC7578R-100UG

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	IC7578U-100UG
Alexa Fluor 488	IC7578G
Alexa Fluor 532	FAB7578X
Alexa Fluor 594	IC7578T-100UG
Alexa Fluor 647	IC7578R-100UG
Alexa Fluor 700	IC7578N
Alexa Fluor 750	IC7578S-100UG
Allophycocyanin	IC7578A
Biotin	FAB7578B
CoraFluor 1	FAB7578CL1
DyLight 350	FAB7578D
DyLight 405	FAB7578E
DyLight 488	FAB7578K
DyLight 550	FAB7578L
DyLight 594	FAB7578M
DyLight 650	FAB7578W
DyLight 680	FAB7578Y
DyLight 755	FAB7578Z
FITC	FAB7578F
HRP	FAB7578H
Janelia Fluor 525	FAB7578JF525
Janelia Fluor 549	FAB7578I
Janelia Fluor 646	FAB7578J
Janelia Fluor 669	FAB7578JF669
Phycoerythrin	IC7578P
mFluor Violet 450 SE	FAB7578MFV450
mFluor Violet 500 SE	FAB7578MFV500
mFluor Violet 610 SE	FAB7578MFV610

NLRP3/NALP3 Antibody (768319) [Unconjugated]

Species Glossary

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NLRP3/NALP3 Antibody (768319) [Unconjugated] Summary

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Alternate Names for NLRP3/NALP3 Antibody (768319) [Unconjugated]

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Publications for NLRP3/NALP3 Antibody (MAB7578)(61)

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Immunogen	E. coli-derived recombinant mouse NLRP3/NALP3 Met1-Arg153 Accession # Q8R4B8
Specificity	Detects mouse NLRP3/NALP3 in direct ELISAs. In direct ELISAs, 100% cross-reactivity with recombinant human NLRP3/NALP3 is observed.
Source	N/A
Isotype	IgG2a
Clonality	Monoclonal
Host	Rat
Gene	NLRP3
Purity Statement	Protein A or G purified from hybridoma culture supernatant
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Concentration	LYOPH
Reconstitution Instructions	Sterile PBS to a final concentration of 0.5 mg/mL.

Publications using MAB7578	Applications	Species
Kim, D;Ban, KY;Lee, GH;Jun, HS; Lysophosphatidic Acid Induces Podocyte Pyroptosis in Diabetic Nephropathy by an Increase of Egr1 Expression via Downregulation of EzH2 International journal of molecular sciences 2023-06-09 [PMID: 37373116] (Immunohistochemistry, Mouse)	Immunohistochemistry	Mouse
Yaodan Zhang, Yuyang Miao, Xiangyang Xiong, Jin Tan, Zhaoli Han, Fanglian Chen et al. Microglial exosomes alleviate intermittent hypoxia-induced cognitive deficits by suppressing NLRP3 inflammasome Biology Direct 6/13/2023 [PMID: 37312196]
Ashley Pitzer Mutchler, Linh Huynh, Ritam Patel, Tracey Lam, Daniel Bain, Sydney Jamison et al. The role of dietary magnesium deficiency in inflammatory hypertension Frontiers in Physiology 5/24/2023 [PMID: 37293263]
H Pazoki, H Mirjalali, M Niyyati, SJ Seyed Taba, N Mosaffa, S Shahrokh, H Asadzadeh, A Kupz, MR Zali Toxoplasma gondii profilin induces NLRP3 activation and IL-1beta production/secretion in THP-1ï¿½cells Microbial pathogenesis, 2023;180(0):106120. 2023 [PMID: 37080500] (Western Blot, Human)	Western Blot	Human
H Pazoki, H Mirjalali, M Niyyati, SJ Seyed Taba, N Mosaffa, S Shahrokh, H Asadzadeh, A Kupz, MR Zali Toxoplasma gondii profilin induces NLRP3 activation and IL-1beta production/secretion in THP-1ï¿½cells Microbial pathogenesis, 2023-04-18;180(0):106120. 2023-04-18 [PMID: 37080500] (Western Blot, Human)	Western Blot	Human
Y Wang, S Pei, Z Liu, Y Ding, T Qian, H Wen, SW Hsu, Z Zhou, J Zhang, H Wang IRAK-M suppresses the activation of microglial NLRP3 inflammasome and GSDMD-mediated pyroptosis through inhibiting IRAK1 phosphorylation during experimental autoimmune encephalomyelitis Cell Death & Disease, 2023-02-10;14(2):103. 2023-02-10 [PMID: 36765034] (IHC, Western Blot, Mouse)	IHC, Western Blot	Mouse
Janneh AH, Kassir MF, Atilgan FC et al. Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis Cell Reports 12/6/2022 [PMID: 36476873]
Janneh AH, Kassir MF, Atilgan FC et al. Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis Cell Reports 2022-12-06 [PMID: 36476873]
TMT Truong, SH Seo, S Chung, I Kang Attenuation of hepatic fibrosis by p-Coumaric acid via modulation of NLRP3 inflammasome activation in C57BL/6 mice The Journal of nutritional biochemistry, 2022-11-15;0(0):109204. 2022-11-15 [PMID: 36400112] (Western Blot, Mouse)	Western Blot	Mouse
S Singh, IA Shaikh, SS More, MH Mahnashi, HM Almohaimee, M El-Sherbin, MM Ghoneim, A Umar, HK Soni, H Agrawal, BA Mannasaheb, AA Khan, UM Muddapur, SMS Iqubal Blockage of KHSRP-NLRP3 by MCC950 Can Reverse the Effect of Manganese-Induced Neuroinflammation in N2a Cells and Rat Brain International Journal of Molecular Sciences, 2022-10-30;23(21):. 2022-10-30 [PMID: 36362011] (Western Blot, Mouse)	Western Blot	Mouse
Xinxu Yuan, Owais M. Bhat, Yao Zou, Xiang Li, Yang Zhang, Pin-Lan Li Endothelial Acid Sphingomyelinase Promotes NLRP3 Inflammasome and Neointima Formation During Hypercholesterolemia Journal of Lipid Research 12/1/2022 [PMID: 36252682]
W Lenga Ma B, M Fournet, R Zhai, J Lutz, R Blondonnet, C Bourgne, C Leclaire, C Saint-Béat, C Theilliere, C Belville, D Bouvier, L Blanchon, M Berger, V Sapin, M Jabaudon Receptor for Advanced Glycation End-Products Promotes Activation of Alveolar Macrophages through the NLRP3 Inflammasome/TXNIP Axis in Acute Lung Injury International Journal of Molecular Sciences, 2022-10-01;23(19):. 10/1/2022 [PMID: 36232959]
F La Rosa, CP Zoia, C Bazzini, A Bolognini, M Saresella, E Conti, C Ferrarese, F Piancone, I Marventano, D Galimberti, C Fenoglio, E Scarpini, M Clerici Modulation of MAPK- and PI3/AKT-Dependent Autophagy Signaling by Stavudine (D4T) in PBMC of Alzheimer's Disease Patients Cells, 2022-07-12;11(14):. 2022-07-12 [PMID: 35883623] (Flow Cytometry, Human)	Flow Cytometry	Human
Alejandro González-Candia, Alejandro A. Candia, Adolfo Paz, Fuad Mobarec, Rodrigo Urbina-Varela, Andrea del del Campo et al. Cardioprotective Antioxidant and Anti-Inflammatory Mechanisms Induced by Intermittent Hypobaric Hypoxia Antioxidants (Basel) 5/25/2022 [PMID: 35739940]
Alice J. West, Virginie Deswaerte, Alison C. West, Linden J. Gearing, Patrick Tan, Brendan J. Jenkins Inflammasome-Associated Gastric Tumorigenesis Is Independent of the NLRP3 Pattern Recognition Receptor Frontiers in Oncology 3/1/2022 [PMID: 35299732]
ES Park, S Kim, DC Yao, JPJ Savarraj, HA Choi, PR Chen, E Kim Soluble Endoglin Stimulates Inflammatory and Angiogenic Responses in Microglia That Are Associated with Endothelial Dysfunction International Journal of Molecular Sciences, 2022-01-22;23(3):. 2022-01-22 [PMID: 35163148] (IHC, Mouse)	IHC	Mouse
Y Zhang, B Hou, P Liang, X Lu, Y Wu, X Zhang, Y Fan, Y Liu, T Chen, W Liu, B Peng, J Yin, S Han, X He TRPV1 channel mediates NLRP3 inflammasome-dependent neuroinflammation in microglia Cell Death & Disease, 2021-12-14;12(12):1159. 2021-12-14 [PMID: 34907173] (ICC, IHC, Western Blot, Mouse)	ICC, IHC, Western Blot	Mouse
N Ma, Z Wei, J Hu, W Gu, X Ci Farrerol Ameliorated Cisplatin-Induced Chronic Kidney Disease Through Mitophagy Induction via Nrf2/PINK1 Pathway Frontiers in Pharmacology, 2021-11-11;12(0):768700. 2021-11-11 [PMID: 34858188] (Western Blot, Mouse)	Western Blot	Mouse
Xenia Kodji, Zizheng Kee, Robyn McKenna, Joao de Sousa Valente, Harriet Ravenscroft, Hayley McMillan et al. Evidence That a TRPA1-Mediated Murine Model of Temporomandibular Joint Pain Involves NLRP3 Inflammasome Activation Pharmaceuticals (Basel) 10/23/2021 [PMID: 34832855]
A Baral, PH Park Leptin Induces Apoptotic and Pyroptotic Cell Death via NLRP3 Inflammasome Activation in Rat Hepatocytes International Journal of Molecular Sciences, 2021-11-22;22(22):. 2021-11-22 [PMID: 34830465] (Western Blots, Rat)	Western Blots	Rat
Yana Liu, Shihong Zhang, Zhiwei Xue, Xiaoxia Zhou, Lin Tong, Jiachen Liao et al. Bone mesenchymal stem cells-derived miR-223-3p-containing exosomes ameliorate lipopolysaccharide-induced acute uterine injury via interacting with endothelial progenitor cells Bioengineered 12/20/2021 [PMID: 34738867]
AL Soung, VA Davé, C Garber, ED Tycksen, LL Vollmer, RS Klein IL-1 reprogramming of adult neural stem cells limits neurocognitive recovery after viral encephalitis by maintaining a proinflammatory state Brain, Behavior, and Immunity, 2021-10-22;0(0):. 2021-10-22 [PMID: 34695572] (IHC, Mouse)	IHC	Mouse
Luan Américo-Da-Silva, Javiera Aguilera, Oscar Quinteros-Waltemath, Pablo Sánchez-Aguilera, Javier Russell, Cynthia Cadagan et al. Activation of the NLRP3 Inflammasome Increases the IL-1 beta Level and Decreases GLUT4 Translocation in Skeletal Muscle during Insulin Resistance International Journal of Molecular Sciences 9/23/2021 [PMID: 34638553]
J Croden, JR Silva, W Huang, N Gupta, W Fu, K Matovinovi, M Black, X Li, K Chen, Y Wu, J Jhamandas, GR Rayat Cyanidin-3-O-Glucoside improves the viability of human islet cells treated with amylin or Abeta1-42 in vitro PLoS ONE, 2021-10-06;16(10):e0258208. 2021-10-06 [PMID: 34614009] (IHC, Mouse)	IHC	Mouse
Enrique Huanosta-Murillo, Marcela Alcántara-Hernández, Brenda Hernández-Rico, Georgina Victoria-Acosta, Patricia Miranda-Cruz, María Antonieta Domínguez-Gómez et al. NLRP3 Regulates IL-4 Expression in TOX+ CD4+ T Cells of Cutaneous T Cell Lymphoma to Potentially Promote Disease Progression Frontiers in Immunology 6/16/2021 [PMID: 34220814]
Cau SB, Bruder-Nascimento A, Silva MB et al. Angiotensin-II activates vascular inflammasome and induces vascular damage Vascular pharmacology 6/9/2021 [PMID: 34098096]
Y Wang, S Chen, PL Yang, JJ Chen, WJ Kong, YJ Wang AIM2 inflammasome activation may mediate high mobility group box 1 release in murine allergic rhinitis Brazilian journal of otorhinolaryngology, 2021-02-15;0(0):. 2021-02-15 [PMID: 33707120] (Western Blot, Mouse)	Western Blot	Mouse
Zhiqin Deng, Zicong Lin, Qing Zhong, Minqiang Lu, Huankun Fang, Jianquan Liu et al. Interleukin 1 beta-induced chloride currents are important in osteoarthritis onset: an in vitro study Acta Biochimica et Biophysica Sinica 3/26/2021 [PMID: 33677475]
G Kaufman, D Skrtic N-Acetyl Cysteine Modulates the Inflammatory and Oxidative Stress Responses of Rescued Growth-Arrested Dental Pulp Microtissues Exposed to TEGDMA in ECM Int J Mol Sci, 2020-10-03;21(19):. 10/3/2020 [PMID: 33023018]
Tian Zhang, Hao Li, Ke Wang, Bing Xu, Zhi-Nan Chen, Huijie Bian Deficiency of CD147 Attenuated Non-alcoholic Steatohepatitis Progression in an NLRP3-Dependent Manner Frontiers in Cell and Developmental Biology 8/13/2020 [PMID: 32903542]
AER Oliveira, MCA Pereira, AT Belew, LRP Ferreira, LMN Pereira, EGA Neves, MDCP Nunes, BA Burleigh, WO Dutra, NM El-Sayed, RT Gazzinelli, SMR Teixeira Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruziï¿½strains unveil a role for fibroblasts in neutrophil recruitment and activation PLoS Pathog., 2020-08-18;16(8):e1008781. 2020-08-18 [PMID: 32810179] (Western Blot, Human)	Western Blot	Human
Hervé Lecoeur, Thibault Rosazza, Kossiwa Kokou, Hugo Varet, Jean-Yves Coppée, Arezou Lari et al. Leishmania amazonensis Subverts the Transcription Factor Landscape in Dendritic Cells to Avoid Inflammasome Activation and Stall Maturation Frontiers in Immunology 6/9/2020 [PMID: 32582184]
S Serini, R Guarino, R Ottes Vasc, L Celleno, G Calviello The Combination of Sulforaphane and Fernblockï¿½ XP Improves Individual Beneficial Effects in Normal and Neoplastic Human Skin Cell Lines Nutrients, 2020-05-30;12(6):. 2020-05-30 [PMID: 32486135] (Western Blot, Human)	Western Blot	Human
B Hou, Y Zhang, P Liang, Y He, B Peng, W Liu, S Han, J Yin, X He Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype Cell Death Dis, 2020-05-15;11(5):377. 2020-05-15 [PMID: 32415059] (Western Blot, Mouse)	Western Blot	Mouse
H Lecoeur, E Prina, T Rosazza, K Kokou, P N'Diaye, N Aulner, H Varet, G Bussotti, Y Xing, G Milon, R Weil, G Meng, GF Späth Targeting Macrophage Histone H3 Modification as a Leishmania Strategy to Dampen the NF-&kappaB/NLRP3-Mediated Inflammatory Response Cell Rep, 2020-02-11;30(6):1870-1882.e4. 2020-02-11 [PMID: 32049017] (Western Blot, Mouse)	Western Blot	Mouse
NS Ferreira, T Bruder-Nas, CA Pereira, CZ Zanotto, DS Prado, JF Silva, DM Rassi, MC Foss-Freit, JC Alves-Filh, D Carlos, RC Tostes NLRP3 Inflammasome and Mineralocorticoid Receptors Are Associated with Vascular Dysfunction in Type 2 Diabetes Mellitus Cells, 2019-12-08;8(12):. 2019-12-08 [PMID: 31817997] (Western Blot, Mouse)	Western Blot	Mouse
CY Chang, HJ Shih, IT Huang, PS Tsai, KY Chen, CJ Huang Magnesium Sulfate Mitigates the Progression of Monocrotaline Pulmonary Hypertension in Rats Int J Mol Sci, 2019-09-18;20(18):. 2019-09-18 [PMID: 31540416] (IHC-P, Rat)	IHC-P	Rat
P Samir, S Kesavardha, DM Patmore, S Gingras, RKS Malireddi, R Karki, CS Guy, B Briard, DE Place, A Bhattachar, BR Sharma, A Nourse, SV King, A Pitre, AR Burton, S Pelletier, RJ Gilbertson, TD Kanneganti DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome Nature, 2019-09-11;0(0):. 2019-09-11 [PMID: 31511697] (ICC, Mouse)	ICC	Mouse
S Serini, R Cassano, E Facchinett, G Amendola, S Trombino, G Calviello Anti-Irritant and Anti-Inflammatory Effects of DHA Encapsulated in Resveratrol-Based Solid Lipid Nanoparticles in Human Keratinocytes Nutrients, 2019-06-21;11(6):. 2019-06-21 [PMID: 31234344] (Western Blot, Human)	Western Blot	Human
Wang Y, Shi P, Chen Q et al. Mitochondrial ROS promote macrophage pyroptosis by inducing GSDMD oxidation J Mol Cell Biol 3/12/2019 [PMID: 30860577]
Fauzia E, Barbhuyan Tk, Shrivastava Ak et al. Chick Embryo: A Preclinical Model for Understanding Ischemia-Reperfusion Mechanism. Front Pharmacol. 9/21/2018 [PMID: 30298003]
GI Lancaster, KG Langley, NA Berglund, HL Kammoun, S Reibe, E Estevez, J Weir, NA Mellett, G Pernes, JRW Conway, MKS Lee, P Timpson, AJ Murphy, SL Masters, S Gerondakis, N Bartonicek, DC Kaczorowsk, ME Dinger, PJ Meikle, PJ Bond, MA Febbraio Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism Cell Metab., 2018-04-19;0(0):. 2018-04-19 [PMID: 29681442] (Western Blot, Mouse)	Western Blot	Mouse
R Boursereau, M Abou-Samra, S Lecompte, L Noel, SM Brichard Downregulation of the NLRP3 inflammasome by adiponectin rescues Duchenne muscular dystrophy BMC Biol., 2018-03-20;16(1):33. 2018-03-20 [PMID: 29558930] (IHC-P, Western Blot, Mouse)	IHC-P, Western Blot	Mouse
A Gugliandol, S Giacoppo, M Ficicchia, A Aliquò, P Bramanti, E Mazzon Eruca sativa seed extract: A novel natural product able to counteract neuroinflammation Mol Med Rep, 2018-03-07;0(0):. 2018-03-07 [PMID: 29512782] (ICC, Mouse)	ICC	Mouse
DM Gong, YL Zhang, DY Chen, LJ Hong, F Han, QB Liu, JJ Jiang, YM Lu Endothelial GPR124 Exaggerates the Pathogenesis of Atherosclerosis by Activating Inflammation Cell. Physiol. Biochem., 2018-01-25;45(2):547-557. 2018-01-25 [PMID: 29402834] (IHC, Mouse)	IHC	Mouse
C Kosmidou, NE Efstathiou, MV Hoang, S Notomi, EK Konstantin, M Hirano, K Takahashi, DE Maidana, P Tsoka, L Young, ES Gragoudas, TW Olsen, Y Morizane, JW Miller, DG Vavvas Issues with the Specificity of Immunological Reagents for NLRP3: Implications for Age-related Macular Degeneration Sci Rep, 2018-01-11;8(1):461. 2018-01-11 [PMID: 29323137] (Western Blot, Mouse)	Western Blot	Mouse
Xuefeng Deng, Wei Zou, Min Xiong, Zekun Wang, John F. Engelhardt, Shui Qing Ye et al. Human Parvovirus Infection of Human Airway Epithelia Induces Pyroptotic Cell Death by Inhibiting Apoptosis Journal of Virology 12/15/2017 [PMID: 29021400]
Sabrina Giacoppo, Placido Bramanti, Emanuela Mazzon Triggering of inflammasome by impaired autophagy in response to acute experimental Parkinson's disease: involvement of the PI3K/Akt/mTOR pathway NeuroReport 10/18/2017 [PMID: 28902711]
SE DeWolf, AA Shigeoka, A Scheinok, SG Kasimsetty, AK Welch, DB McKay Expression of TLR2, NOD1, and NOD2 and the NLRP3 Inflammasome in Renal Tubular Epithelial Cells of Male versus Female Mice Nephron, 2017-06-15;0(0):. 2017-06-15 [PMID: 28614830] (Western Blot, Mouse)	Western Blot	Mouse
AM Yang, T Inamine, K Hochrath, P Chen, L Wang, C Llorente, S Bluemel, P Hartmann, J Xu, Y Koyama, T Kisseleva, MG Torralba, K Moncera, K Beeri, CS Chen, K Freese, C Hellerbran, SM Lee, HM Hoffman, WZ Mehal, G Garcia-Tsa, EA Mutlu, A Keshavarzi, GD Brown, SB Ho, R Bataller, P Stärkel, DE Fouts, B Schnabl Intestinal fungi contribute to development of alcoholic liver disease J. Clin. Invest., 2017-05-22;0(0):. 2017-05-22 [PMID: 28530644] (Western Blot, Mouse)	Western Blot	Mouse
D Daley, VR Mani, N Mohan, N Akkad, GSDB Pandian, S Savadkar, KB Lee, A Torres-Her, B Aykut, B Diskin, W Wang, MS Farooq, AI Mahmud, G Werba, EJ Morales, S Lall, BJ Wadowski, AG Rubin, ME Berman, R Narayanan, M Hundeyin, G Miller NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma J. Exp. Med., 2017-04-25;0(0):. 2017-04-25 [PMID: 28442553] (Flow Cytometry, IHC, IHC-P, Human, Mouse)	Flow Cytometry, IHC, IHC-P	Human, Mouse
X Chen, N Wang, Y Zhu, Y Lu, X Liu, J Zheng The Antimalarial Chloroquine Suppresses LPS-Induced NLRP3 Inflammasome Activation and Confers Protection against Murine Endotoxic Shock Mediators Inflamm., 2017-02-22;2017(0):6543237. 2017-02-22 [PMID: 28321151] (Western Blot, Mouse)	Western Blot	Mouse
F Bian, Y Xiao, M Zaheer, EA Volpe, SC Pflugfelde, DQ Li, CS de Paiva Inhibition of NLRP3 Inflammasome Pathway by Butyrate Improves Corneal Wound Healing in Corneal Alkali Burn Int J Mol Sci, 2017-03-05;18(3):. 2017-03-05 [PMID: 28273882] (IHC-Fr, Western Blot, Mouse)	IHC-Fr, Western Blot	Mouse
Knockout of Ccr2 alleviates photoreceptor cell death in rodent retina exposed to chronic blue light Cell Death Dis, 2016-11-10;7(11):e2468. 2016-11-10 [PMID: 27831552] (IHC-Fr, Mouse)	IHC-Fr	Mouse
Rithwick Rajagopal, Gregory W. Bligard, Sheng Zhang, Li Yin, Peter Lukasiewicz, Clay F. Semenkovich Functional Deficits Precede Structural Lesions in Mice With High-Fat Diet–Induced Diabetic Retinopathy Diabetes 4/1/2016 [PMID: 26740595]
Kim Y, Wang W, Okla M, Kang I, Moreau R, Chung S Suppression of NLRP3 inflammasome by gamma-tocotrienol ameliorates type 2 diabetes. J Lipid Res, 2015-12-01;57(1):66-76. 2015-12-01 [PMID: 26628639] (Western Blot, Mouse)	Western Blot	Mouse
Liu X, Hu Z, Zhou B, Li X, Tao R Chinese Herbal Preparation Xuebijing Potently Inhibits Inflammasome Activation in Hepatocytes and Ameliorates Mouse Liver Ischemia-Reperfusion Injury. PLoS ONE, 2015-07-01;10(7):e0131436. 2015-07-01 [PMID: 26132490] (Western Blot, Mouse)	Western Blot	Mouse
Antonopoulos C, Russo H, El Sanadi C, Martin B, Li X, Kaiser W, Mocarski E, Dubyak G Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling. J Biol Chem, 2015-06-22;290(33):20167-84. 2015-06-22 [PMID: 26100631] (Western Blot, Mouse)	Western Blot	Mouse
Vincent M. Bruno, Amol C. Shetty, Junko Yano, Paul L. Fidel, Mairi C. Noverr, Brian M. Peters Transcriptomic Analysis of Vulvovaginal Candidiasis Identifies a Role for the NLRP3 Inflammasome mBio 5/1/2015 [PMID: 25900651]
Maier N, Leppla S, Moayeri M The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes. J Immunol, 2015-02-13;194(6):2776-85. 2015-02-13 [PMID: 25681332] (Immunoprecipitation, Mouse)	Immunoprecipitation	Mouse
Komada T, Usui F, Shirasuna K, Kawashima A, Kimura H, Karasawa T, Nishimura S, Sagara J, Noda T, Taniguchi S, Muto S, Nagata D, Kusano E, Takahashi M ASC in renal collecting duct epithelial cells contributes to inflammation and injury after unilateral ureteral obstruction. Am J Pathol, 2014-03-05;184(5):1287-98. 2014-03-05 [PMID: 24606883] (Western Blot, Mouse)	Western Blot	Mouse
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Gene Symbol	NLRP3
Uniprot	Q8R4B8()