Nestin Antibody (307501) [Phycoerythrin]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Nestin is a class VI intermediate filament protein (1,2) that is expressed in stem cells of the central nervous system (CNS) (3) but not in mature CNS cells.(4) Nestin expression is used extensively as a marker for CNS stem cells in the developing nervous system and in vitro cultured cells (5-10). Its transient expression is a critical step in the neural differentiation pathway.(2) Nestin is also expressed in non-neural stem cell populations, such as pancreatic islet progenitors (11-13) and hematopoietic progenitors (14). Over amino acids (aa) 544-820, rat Nestin shares 75% and 38% sequence identity with mouse and human Nestin, respectively.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: Flow Cytometry.

Showing Publications 1 - 8 of 8.

Publications using IC2736P	Applications	Species
Joanna M. Gould, Phoebe J. Smith, Chris J. Airey, Emily J. Mort, Lauren E. Airey, Frazer D. M. Warricker et al. Mouse maternal protein restriction during preimplantation alone permanently alters brain neuron proportion and adult short-term memory Proceedings of the National Academy of Sciences 7/31/2018 [PMID: 29941596]
Xiaochun Teng, Yan-Yun Liu, Weiping Teng, Gregory A. Brent COUP-TF1 Modulates Thyroid Hormone Action in an Embryonic Stem-Cell Model of Cortical Pyramidal Neuronal Differentiation Thyroid 5/1/2018 [PMID: 29205104]
P Wang, C Lan, S Xiong, X Zhao, Y Shan, R Hu, W Wan, S Yu, B Liao, G Li, J Wang, D Zou, B Chen, H Feng, N Wu HIF1? regulates single differentiated glioma cell dedifferentiation to stem-like cell phenotypes with high tumorigenic potential under hypoxia Oncotarget, 2017-04-25;8(17):28074-28092. 2017-04-25 [PMID: 28427209] (Flow Cytometry, Human)	Flow Cytometry	Human
Y Wang, X Ying, H Xu, H Yan, X Li, H Tang The functional curcumin liposomes induce apoptosis in C6 glioblastoma cells and C6 glioblastoma stem cells in vitro and in animals Int J Nanomedicine, 2017-02-17;12(0):1369-1384. 2017-02-17 [PMID: 28260885] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Apurva Kulkarni, Taylor J. Scully, Lauren A. O'Donnell The antiviral cytokine interferon-gamma restricts neural stem/progenitor cell proliferation through activation of STAT1 and modulation of retinoblastoma protein phosphorylation Journal of Neuroscience Research 8/1/2017 [PMID: 27862183]
Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile J Immunol, 2016-04-29;196(11):4760-70. 2016-04-29 [PMID: 27183606] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Hu S, Rotschafer J, Lokensgard J, Cheeran M Activated CD8+ T lymphocytes inhibit neural stem/progenitor cell proliferation: role of interferon-gamma. PLoS ONE, 2014-08-18;9(8):e105219. 2014-08-18 [PMID: 25133679] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Mutnal MB, Cheeran MC, Hu S Murine cytomegalovirus infection of neural stem cells alters neurogenesis in the developing brain. PLoS ONE, 2011-01-13;6(1):e16211. 2011-01-13 [PMID: 21249143] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse

Array IC2736P

• Nestin Antibodies
• Nestin ELISA Kits
• Nestin Proteins