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MP1/MAP2K1IP1 Antibody

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Western Blot: MP1/MAP2K1IP1 Antibody [NBP2-87818] - Host: Rabbit. Target Name: LAMTOR3. Sample Type: 293T Whole Cell lysates. Antibody Dilution: 1.0ug/mlLAMTOR3 is supported by BioGPS gene expression data to be ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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MP1/MAP2K1IP1 Antibody Summary

Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human MP1/MAP2K1IP1. Peptide sequence: LPSVEGLHAIVVSDRDGVPVIKVANDNAPEHALRPGFLSTFALATDQGSK The peptide sequence for this immunogen was taken from within the described region.
Clonality
Polyclonal
Host
Rabbit
Gene
LAMTOR3
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1.0 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for MP1/MAP2K1IP1 Antibody

  • LAMTOR3
  • Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3
  • late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
  • MAP2K1IP1
  • Mapbp
  • MAPK scaffold protein 1
  • MAPKSP1
  • MEK binding partner 1
  • MEK partner 1
  • MEK-binding partner 1
  • mitogen-activated protein kinase kinase 1 interacting protein 1
  • Mitogen-activated protein kinase kinase 1-interacting protein 1
  • Mitogen-activated protein kinase scaffold protein 1
  • MP1
  • PRO0633
  • Ragulator3

Background

The function of MAP2K1IP1/MAPKSP1 (MP1;MEK partner-1) a 14kDa scaffold protein, is to bind specifically to MEK1 and ERK1 and bring them in close proximity in order to facilitate their activation. Localized to the late endosome, MAP2K1IP1 also interacts with an adaptor protein p14. While the interaction between MAPKSP1-ERK1 can take place in the absence of the adaptor protein p14, it is strengthened in the presence of p14. Additionally, it has been suggested that the binding of MAP2K1IP1/MAPKSP1 to MEK1 resides in a proline-rich sequence (residue 270-307) of MEK1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol LAMTOR3