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Monoglyceride Lipase Antibody

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Immunohistochemistry-Paraffin: Monoglyceride Lipase Antibody [NBP1-89646] - Staining of human testis shows cytoplasmic positivity in cells in seminiferous ducts and Leydig cells.
Immunohistochemistry-Paraffin: Monoglyceride Lipase Antibody [NBP1-89646] - Staining of human testis shows cytoplasmic positivity in cells in seminiferous ducts and Leydig cells.
Immunohistochemistry-Paraffin: Monoglyceride Lipase Antibody [NBP1-89646] - Staining of human colon shows cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: Monoglyceride Lipase Antibody [NBP1-89646] - Staining of human kidney shows cytoplasmic positivity in cells in tubules.
Immunohistochemistry-Paraffin: Monoglyceride Lipase Antibody [NBP1-89646] - Staining of human placenta shows cytoplasmic positivity in trophoblastic cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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Monoglyceride Lipase Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: RQHIMETGPEDPSSMPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSM
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MGLL
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Monoglyceride Lipase Protein (NBP1-89646PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (84%), Rat (82%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Monoglyceride Lipase Antibody

  • HUK5
  • HU-K5EC 3.1.1.23
  • Lysophospholipase homolog
  • Lysophospholipase-like
  • MAGL
  • MGLHUK5
  • MGLL
  • Monoacylglycerol lipase
  • Monoglyceride Lipase

Background

Monoglyceride lipase (MGLL; EC 3.1.1.23) functions together with hormone-sensitive lipase (LIPE; MIM 151750) to hydrolyze intracellular triglyceride stores in adipocytes and other cells to fatty acids and glycerol. MGLL may also complement lipoprotein lipase (LPL; MIM 238600) in completing hydrolysis of monoglycerides resulting from degradation of lipoprotein triglycerides (Karlsson et al., 2001 [PubMed 11470505]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MGLL