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MLL3 Antibody

Images

 
Staining of human cell line SiHa shows localization to nucleoplasm.
Analysis in human cell line RT-4 and human cell line U-251 MG.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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MLL3 Antibody Summary

Immunogen
This antibody has been engineered to specifically recognize the recombinant protein MLL3 using the following amino acid sequence: DTQLKEEYICMYCKHLGAEMDRLQPGEEVEIAELTTDYNNEMEVEGPEDQMVFSEQAANKDVNGQESTPGIVPDAVQVHTEEQQKSHPSESL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KMT2C
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 µg/ml
  • Western Blot 0.04-0.4 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.2, 40% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for MLL3 Antibody

  • ALR-like protein
  • DKFZp686C08112
  • EC 2.1.1.43
  • FLJ12625
  • HALRMGC119851
  • histone-lysine N-methyltransferase MLL3
  • histone-lysine N-methyltransferase, H3 lysine-4 specific
  • Homologous to ALR protein
  • KIAA1506FLJ38309
  • KMT2C
  • KMT2CMGC119852
  • Lysine N-methyltransferase 2C
  • MGC119853
  • myeloid/lymphoid or mixed-lineage leukemia 3
  • Myeloid/lymphoid or mixed-lineage leukemia protein 3

Background

The MLL3 gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a nuclear protein withan AT hook DNA-binding domain, a DHHC-type zinc finger, six PHD-type zinc fingers, a SET domain, a post-SET domain anda RING-type zinc f

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol KMT2C