GFER/ALR Antibody (829812)

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

GFER, also known as Augmenter of Liver Regeneration (ALR) and Hepatopoietin, is an approximately 30 kDa mitochondrial sulfhydryl oxidase that plays a role in protein disulfide bond formation. Alternative splicing of human GFER generates a 15 kDa secreted isoform that lacks the 80 N-terminal amino acids. Within aa 82‑205, human GFER shares approximately 86% aa sequence identity with mouse and rat GFER. GFER protects hepatocytes from toxin-induced damage, promotes hepatic regeneration, and inhibits the metastasis of hepatocellular carcinoma. It also restricts the proliferation of pluripotent and hematopoietic stem cells and maintains mitochondrial integrity.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: IHC-P.

Showing Publication 1 - 1 of 1.

Publication using MAB7940	Applications	Species
C Sima, E Montero, D Nguyen, M Freire, P Norris, CN Serhan, TE Van Dyke ERV1 Overexpression in Myeloid Cells Protects against High Fat Diet Induced Obesity and Glucose Intolerance Sci Rep, 2017-10-09;7(1):12848. 2017-10-09 [PMID: 28993702] (IHC-P, Mouse)	IHC-P	Mouse

Array MAB7940

• GFER/ALR Antibodies
• GFER/ALR Proteins