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Melan-A/MART-1 Antibody (MLANA/788) [DyLight 650]

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Product Details

Summary
Reactivity Hu, Mu, Rt, CaSpecies Glossary
Applications WB, Flow, IHC, CyTOF-ready
Clone
MLANA/788
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 650

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-47803AF350
Alexa Fluor 405
NBP2-47803AF405
Alexa Fluor 488
NBP2-47803AF488
Alexa Fluor 532
NBP2-47803AF532
Alexa Fluor 594
NBP2-47803AF594
Alexa Fluor 647
NBP2-47803AF647
Alexa Fluor 700
NBP2-47803AF700
Alexa Fluor 750
NBP2-47803AF750
Allophycocyanin
NBP2-47803APC
Allophycocyanin/Cy7
NBP2-47803APCCY7
Biotin
NBP2-47803B
CoraFluor 1
NBP2-47803CL1
DyLight 350
NBP2-47803UV
DyLight 405
NBP2-47803V
DyLight 488
NBP2-47803G
DyLight 550
NBP2-47803R
DyLight 594
NBP2-47803DL594
DyLight 680
NBP2-47803FR
DyLight 755
NBP2-47803IR
FITC
NBP2-47803F
HRP
NBP2-47803H
Janelia Fluor 525
NBP2-47803JF525
Janelia Fluor 549
NBP2-47803JF549
Janelia Fluor 585
NBP2-47803JF585
Janelia Fluor 635
NBP2-47803JF635
Janelia Fluor 646
NBP2-47803JF646
Janelia Fluor 669
NBP2-47803JF669
PE
NBP2-47803PE
PE/Atto594
NBP2-47803PEATT594
PE/Cy5.5
NBP2-47803PECY55
PE/Cy7
NBP2-47803PECY7
PerCP
NBP2-47803PCP
Unconjugated
NBP2-44394-0.1mg
mFluor Violet 450 SE
NBP2-47803MFV450
mFluor Violet 500 SE
NBP2-47803MFV500
mFluor Violet 610 SE
NBP2-47803MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-44394-0.1mg
Azide and BSA Free
NBP2-47803-0.1mg
IHC-Prediluted
NBP2-48209
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Melan-A/MART-1 Antibody (MLANA/788) [DyLight 650] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
Recombinant human full-length Melan-A/MART-1 protein (Uniprot: Q16655)
Localization
Cytoplasmic
Marker
Melanoma Marker
Specificity
This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This monoclonal antibody labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MLANA
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow (Intracellular)
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Melan-A/MART-1 Antibody (MLANA/788) [DyLight 650]

  • Antigen LB39-AA
  • Antigen SK29-AA
  • Mart 1 Melan A
  • MART-1
  • MART1MART-1
  • MelanA
  • Melan-A
  • melanoma antigen recognized by T-cells 1
  • MLANA
  • Protein Melan-A

Background

MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MLANA