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Lyl1 Antibody

Images

 
Western Blot: Lyl1 Antibody [NBP2-27188] - analysis of Lyl1. Lanes 1 and 2 show human HEPG2 cell lysate probed with pre-immune sera (1:5000) and Lyl polyclonal antibody (4 ug/ml), respectively, and lane 3 shows mouse ...read more
Simple Western: Lyl1 Antibody [NBP2-27188] - Simple Western lane view shows a specific band for Lyl1 in 0.5 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation ...read more

Product Details

Summary
Reactivity Hu, Po, Ca, PmSpecies Glossary
Applications WB, Simple Western
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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Lyl1 Antibody Summary

Immunogen
235 RSQPAPPADPDGSPGG 250
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
LYL1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Simple Western 1:10
  • Western Blot 3-5ug/ml
Application Notes
In Simple Western only 10 - 15 uL of the recommended dilution is used per data point. Separated by Size.

Reactivity Notes

Orangutan, Wild pig

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS containing 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for Lyl1 Antibody

  • BHLHA18
  • bHLHa18Class A basic helix-loop-helix protein 18
  • lymphoblastic leukemia derived sequence 1
  • Lymphoblastic leukemia-derived sequence 1
  • protein lyl-1

Background

Protein lyl-1 belongs to basic helix-loop-helix (bHLH) family of proteins and contains a basic helix-loop-helix transcription factor involved in T-cell acute lymphoblastic leukemia. It is reported expression of LYL1 was at higher levels in the majority cases of acute myeloblastic leukemia (AML) or myelodysplastic syndrome when compared to normal bone marrow. Thus LYL1 may play a role in early hematopoiesis and may be a potential oncogenic factor in AML. It is also reported LYL1 are aberrantly over-expressed in leukemia as a result of chromosomal translocations, or other genetic or epigenetic events.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

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Bioinformatics

Gene Symbol LYL1