MAN2B1 Antibody Summary
Immunogen |
Immunized with recombinant Human MAN2B1 (Uniprot#: O00754; Ala883-Gly1011 (Uniprot#: O00754) |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
MAN2B1 |
Purity |
Antigen and protein A Affinity-purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/ Immunofluorescence 5-20ug/mL
- Immunohistochemistry 5-20ug/mL
- Western Blot 0.2-2ug/mL
|
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
PBS, pH7.4, 50% glycerol |
Preservative |
0.02% Sodium Azide |
Concentration |
0.5 mg/ml |
Purity |
Antigen and protein A Affinity-purified |
Alternate Names for MAN2B1 Antibody
Background
MAN2B1 encodes an enzyme that hydrolyzes terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. Its activity is necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover and it is member of family 38 of glycosyl hydrolases. The full length protein is processed in two steps. First, a 49 aa leader sequence is cleaved off and the remainder of the protein is processed into 3 peptides of 70 kDa, 42 kDa (D) and 13/15 kDa (E). Next, the 70 kDa peptide is further processed into three peptides (A, B and C). The A, B and C peptides are disulfide-linked. Defects in this gene have been associated with lysosomal alpha-mannosidosis. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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