LINGO-1 Antibody (332237) [Janelia Fluor® 669] Summary
Immunogen |
Mouse myeloma cell line NS0-derived recombinant human LINGO-1 Thr40-Thr556 Accession # NP_116197 |
Specificity |
Detects human LINGO-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant human (rh) LINGO-2 is observed and no cross-reactivity with rhLINGO-3 is observed. |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
LINGO1 |
Purity |
Protein A or G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- CyTOF-ready
- Flow Cytometry
- Immunocytochemistry
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A or G purified |
Notes
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
Alternate Names for LINGO-1 Antibody (332237) [Janelia Fluor® 669]
Background
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible forsome inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator ofoligodentrocyte differentiation and axonal myelination
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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