LINGO-1 Antibody (332237) [HRP]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready, ICC/IF
Clone
332237
Clonality
Monoclonal
Host
Mouse
Conjugate
HRP

Order Details

LINGO-1 Antibody (332237) [HRP] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human LINGO-1
Thr40-Thr556
Accession # NP_116197
Specificity
Detects human LINGO-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant human (rh) LINGO-2 is observed and no cross-reactivity with rhLINGO-3 is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
LINGO1
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for LINGO-1 Antibody (332237) [HRP]

  • FLJ14594
  • LERN1
  • LERN1UNQ201
  • leucine rich repeat and Ig domain containing 1
  • leucine rich repeat neuronal 6A
  • Leucine-rich repeat and immunoglobilin domain-containing protein 1
  • Leucine-rich repeat neuronal protein 1
  • Leucine-rich repeat neuronal protein 6A
  • LINGO1
  • LINGO-1
  • LRRN6A
  • LRRN6Aleucine-rich repeat neuronal 6A
  • MGC17422

Background

Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible forsome inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator ofoligodentrocyte differentiation and axonal myelination

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol LINGO1