LCAT Antibody

Lecithin: cholesterol acyltransferase (LCAT) is the plasma enzyme responsible for most HDL cholesteryl esters in human plasma. In species with cholesteryl ester transfer protein (CETP) it is also responsible for a significant proportion of VLDL and LDL cholesteryl esters. LCAT, through the esterification of cholesterol, plays a role in the reverse cholesterol transport pathway by facilitating the net movement of cholesterol from peripheral tissues back to the liver for excretion. LCAT deficiency results in low levels of plasma HDL, whereas a transgenic overexpression of LCAT results in increased plasma HDL concentrations.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: ELISA, WB.

Showing Publications 1 - 7 of 7.

Publications using NB400-107	Applications	Species
Aso M, Yamamoto T, Kuroda M et al. First-in-human autologous implantation of genetically modified adipocytes expressing LCAT for the treatment of familial LCAT deficiency Heliyon 2022-11-01 [PMID: 36387451] (WB, Human)	WB	Human
Sasaki M, Delawary M, Sakurai H et al. Novel LCAT (Lecithin:Cholesterol Acyltransferase) Activator DS-8190a Prevents the Progression of Plaque Accumulation in Atherosclerosis Models Arterioscler Thromb Vasc Biol 2020-10-22 [PMID: 33086872] (WB, Human)	WB	Human
Khan AMAM, Hauk VJ, Ibrahim M et al. Caldicellulosiruptor bescii adheres to polysaccharides using a type IV pilin-dependent mechanism Appl. Environ. Microbiol. 2020-02-21 [PMID: 32086304] (WB)	WB
Tanigawa H, Billheimer JT, Tohyama J-i et al. Lecithin: Cholesterol Acyltransferase Expression Has Minimal Effects on Macrophage Reverse Cholesterol Transport In Vivo. Circulation;120(2):160-169. 2009-01-01 [PMID: 19564558] (WB, Human)	WB	Human
He Y, Greene DJ, Kinter M et al. Control of cholesteryl ester transfer protein activity by sequestration of lipid transfer inhibitor protein in an inactive complex. J Lipid Res;49(7):1529-1537. 2008-01-01 [PMID: 18369235] (WB, Human)	WB	Human
Zhao Y, Gebre AK, Parks JS. Amino acids 149 and 294 of human lecithin:cholesterol acyltransferase affect fatty acyl specificity. J Lipid Res;45(12):2310-6. 2004-12-01 [PMID: 15375182] (ELISA, Human)	ELISA	Human
Chisholm JW, Gebre AK, Parks JS. Characterization of C-terminal histidine-tagged human recombinant lecithin:cholesterol acyltransferase. J Lipid Res;40(8):1512-9. 1999-08-01 [PMID: 10428989]

Array NB400-107

• LCAT Antibodies
• LCAT ELISA Kits
• LCAT Lysate
• LCAT Proteins