LCAT Products

Description

Lecithin-Cholesterol Acyltransferase (LCAT) is the plasma enzyme responsible for most HDL cholesteryl esters in human plasma. In species with cholesteryl ester transfer protein (CETP) it is also responsible for a significant proportion of VLDL and LDL cholesteryl esters. LCAT, through the esterification of cholesterol, plays a role in the reverse cholesterol transport pathway by facilitating the net movement of cholesterol from peripheral tissues back to the liver for excretion. LCAT deficiency results in low levels of plasma HDL, whereas a transgenic overexpression of LCAT results in increased plasma HDL concentrations.

LCAT antibodies are useful tools for lipid and cholesterol metabolism research.

Bioinformatics

Entrez	16816 Mouse 3931 Human
Uniprot	AAH14781 Human NM_000229 Human NP_000220.1 Human P04180 Human
Product By Gene ID	3931
Alternate Names	EC 2.3.1.43 lecithin-cholesterol acyltransferasePhospholipid-cholesterol acyltransferase phosphatidylcholine-sterol acyltransferase

Research Areas for LCAT

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cholesterol Metabolism
Lipid and Metabolism
Signal Transduction