Western Blot: KDM2B Antibody (5G1) [H00084678-M09] - Western Blot analysis of FBXL10 expression in Hela NE ( Cat # L013V3 ).
Immunocytochemistry/ Immunofluorescence: KDM2B Antibody (5G1) [H00084678-M09] - Analysis of monoclonal antibody to FBXL10 on HeLa cell. Antibody concentration 10 ug/ml
Sandwich ELISA: KDM2B Antibody (5G1) [H00084678-M09] - Detection limit for recombinant GST tagged FBXL10 is approximately 0.1ng/ml as a capture antibody.
FBXL10 (NP_115979, 457 a.a. ~ 555 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. LGKKPKAPALRFLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVEKLESLPENKKCVPEGIEDPQALLEGVKNVLKEH
Specificity
FBXL10 - F-box and leucine-rich repeat protein 10
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
KDM2B
Purity
IgG purified
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Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for KDM2B Antibody (5G1)
[Histone-H3]-lysine-36 demethylase 1B
CXXC2
CXXC2F-box protein FBL10
CXXC-type zinc finger protein 2
FBL10
F-box and leucine-rich repeat protein 10JEMMA (Jumonji domain, EMSY-interactor, methyltransferase motif) protein
F-box protein FBL10
FBXL10
JHDM1B
JHDM1BF-box/LRR-repeat protein 10
JmjC domain-containing histone demethylation protein 1B
jumonji C domain-containing histone demethylase 1B
Jumonji domain-containing EMSY-interactor methyltransferase motif protein
KDM2B
lysine (K)-specific demethylase 2B
lysine-specific demethylase 2B
NDY1
PCCX2
PCCX2EC 1.14.11.27
protein containing CXXC domain 2
Protein JEMMA
Protein-containing CXXC domain 2
Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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