RNF2 Antibody (6C2)

This product is produced by and distributed for Abnova, a company based in Taiwan.

Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 4 of 4.

Publications using H00006045-M01	Applications	Species
Yasunaga S, Ohtsubo M, Ohno Y et al. Scmh1 Has E3 Ubiquitin Ligase Activity for Geminin and Histone H2A and Regulates Geminin Stability Directly or Indirectly via Transcriptional Repression of Hoxa9 and Hoxb4. Mol Cell Biol. 2012-12-03 [PMID: 23207902]
Gascue C, Tan PL, Cardenas-Rodriguez M et al. Direct role of Bardet-Biedl syndrome proteins in transcriptional regulation. J Cell Sci. 2012-01-15 [PMID: 22302990]
Rugg-Gunn PJ, Cox BJ, Ralston A, Rossant J. Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo. Proc Natl Acad Sci U S A 107(24):10783-90. 2010-06-15 [PMID: 20479220]
Ohtsubo M, Yasunaga S, Ohno Y et al. Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity. Proc Natl Acad Sci U S A;105(30):10396-401. 2008-07-29 [PMID: 18650381]

Array H00006045-M01

• RNF2 Antibodies
• RNF2 Lysate
• RNF2 Proteins