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KDEL Antibody (2C1) [DyLight 680]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clone
2C1
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 680

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 405
NBP2-61926AF405
Alexa Fluor 488
NBP2-61926AF488
Alexa Fluor 647
NBP2-61926AF647
Alexa Fluor 700
NBP2-61926AF700
Biotin
NBP2-61926B
DyLight 350
NBP2-61926UV
DyLight 405
NBP2-61926V
DyLight 488
NBP2-61926G
DyLight 550
NBP2-61926R
DyLight 650
NBP2-61926C
DyLight 755
NBP2-61926IR
HRP
NBP2-61926H
Unconjugated
NBP2-61926
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KDEL Antibody (2C1) [DyLight 680] Summary

Immunogen
KDEL peptide (C-AVKDEL -COOH) conjugated at the N-terminal to Bovine Serum Albumin (BSA)
Specificity
Detects KDEL tagged proteins.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
POGLUT2
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for KDEL Antibody (2C1) [DyLight 680]

  • Endoplasmic reticulum resident protein 58
  • EP58KDEL1
  • ER protein 58
  • ERp58
  • KDEL (Lys-Asp-Glu-Leu) containing 1
  • KDEL motif-containing 1
  • KDEL motif-containing protein 1
  • MGC5302

Background

The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble endoplasmic reticulum (ER) resident proteins and some membrane proteins. 78 and 94 kDa glucose regulated proteins (GRP 78) and GRP 94 respectively and protein disulfide isomerase (PDI) all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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KDEL Antibody
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NBP2-61926FR
KDEL Antibody (2C1) [DyLight 680]
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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol POGLUT2