Factor IX Antibody

This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. Coagulation factor IX is a single chain polypeptide. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Normal concentrations of factor IX in human plasma is app. 3 ug/ml.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array NBP1-33581

• Factor IX Antibodies
• Factor IX Antibody Pair
• Factor IX ELISA Kits
• Factor IX Lysate
• Factor IX Proteins and Enzyme