![Immunohistochemistry-Paraffin: Integrin beta 2/CD18 Antibody [NBP1-88127] - Analysis in human lymph node and skeletal muscle tissues. Corresponding Integrin beta 2/CD18 RNA-seq data are presented for the same tissues.](http://images.novusbio.com/fullsize/Integrin-beta-2-CD18-Antibody-Immunohistochemistry-Paraffin-NBP1-88127-img0014.jpg "Immunohistochemistry-Paraffin: Integrin beta 2/CD18 Antibody [NBP1-88127] - Analysis in human lymph node and skeletal muscle tissues. Corresponding Integrin beta 2/CD18 RNA-seq data are presented for the same tissues.")
| Reactivity | HuSpecies Glossary |
| Applications | WB, ICC/IF, IHC |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugate | Unconjugated |
| Immunogen | This antibody was developed against Recombinant Protein corresponding to amino acids: LEDNLYKRSNEFDYPSVGQLAHKLAENNIQPIFAVTSRMVKTYEKLTEIIPKSAVGELSEDSSNVVHLIKNAYNKLSSRVFLDHNALPDTLKVTYDSFCSNGV |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Rabbit |
| Gene | ITGB2 |
| Purity | Immunogen affinity purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
|
||
| Application Notes | For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100. |
||
| Control Peptide |
|
| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Buffer | PBS (pH 7.2) and 40% Glycerol |
| Preservative | 0.02% Sodium Azide |
| Purity | Immunogen affinity purified |
![Flow Cytometry L-Selectin/CD62L Antibody (4G8) [Unconjugated]](https://images.novusbio.com/images/antibody/bba24_human-l-selectin-cd62l-mab-cl-4g8-flow-cytometry-822024174319..jpg)
![Immunohistochemistry E-Selectin/CD62E Antibody (BBIG-E4) [Unconjugated]](https://images.novusbio.com/images2/E-Selectin_BBA16_Immunohistochemistry_6938.jpg)
![Immunocytochemistry E-Selectin/CD62E Antibody (BBIG-E4) [Unconjugated]](https://images.novusbio.com/images2/E-Selectin_BBA16_Immunocytochemistry_9821.jpg)
![Flow Cytometry E-Selectin/CD62E Antibody (BBIG-E4) [Unconjugated]](https://images.novusbio.com/images2/bba16_human-e-selectin-cd62e-mab-clone-bbig-e4-flow-cytometry-25102021144214.jpg)
Secondary Antibodies |
Isotype Controls |
Research Areas for Integrin beta 2/CD18 Antibody (NBP1-88127)Find related products by research area.
|
|
CD11b/CD18 and Neutrophil-Epithelial Interactions as Targets for Anti-Inflammatory Therapies The beta-2 integrins, a family of four cell surface transmembrane glycoproteins expressed only on leukocytes, include CD11a/CD18, CD11b/CD18, CD11c/CD18, and CD11d/CD18. They consist of a common beta subunit (CD18) and homologous alpha subunits (CD11a... Read full blog post. |
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
| Gene Symbol | ITGB2 |
![Immunohistochemistry-Paraffin: Integrin beta 2/CD18 Antibody [NBP1-88127] - Staining of human gastrointestinal, lymph node, skeletal muscle and tonsil using Anti-Integrin beta 2/CD18 antibody NBP1-88127 (A) shows similar protein distribution across tissues to independent antibody NBP1-88128 (B).](http://images.novusbio.com/fullsize/Integrin-beta-2-CD18-Antibody-Immunohistochemistry-Paraffin-NBP1-88127-img0016.jpg "Immunohistochemistry-Paraffin: Integrin beta 2/CD18 Antibody [NBP1-88127] - Staining of human gastrointestinal, lymph node, skeletal muscle and tonsil using Anti-Integrin beta 2/CD18 antibody NBP1-88127 (A) shows similar protein distribution across tissues to independent antibody NBP1-88128 (B).")
![Western Blot: Integrin beta 2/CD18 Antibody [NBP1-88127] - Analysis using Anti-ITGB2 antibody NBP1-88127 (A) shows similar pattern to independent antibody NBP1-88128 (B).](http://images.novusbio.com/fullsize/Integrin-beta-2-CD18-Antibody-Western-Blot-NBP1-88127-img0011.jpg "Western Blot: Integrin beta 2/CD18 Antibody [NBP1-88127] - Analysis using Anti-ITGB2 antibody NBP1-88127 (A) shows similar pattern to independent antibody NBP1-88128 (B).")
![Immunocytochemistry/Immunofluorescence: Integrin beta 2/CD18 Antibody [NBP1-88127] - Staining of human cell line U-2 OS shows localization to plasma membrane. Antibody staining is shown in green.](http://images.novusbio.com/fullsize/Integrin-beta-2-CD18-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-88127-img0009.jpg "Immunocytochemistry/Immunofluorescence: Integrin beta 2/CD18 Antibody [NBP1-88127] - Staining of human cell line U-2 OS shows localization to plasma membrane. Antibody staining is shown in green.")
![Immunohistochemistry-Paraffin: Integrin beta 2/CD18 Antibody [NBP1-88127] - Staining of human colon shows strong membranous positivity in lymphoid cells.](http://images.novusbio.com/fullsize/Integrin-beta-2-CD18-Antibody-Immunohistochemistry-Paraffin-NBP1-88127-img0015.jpg "Immunohistochemistry-Paraffin: Integrin beta 2/CD18 Antibody [NBP1-88127] - Staining of human colon shows strong membranous positivity in lymphoid cells.")
![Immunohistochemistry-Paraffin: Integrin beta 2/CD18 Antibody [NBP1-88127] - Staining of human skeletal muscle shows no positivity in myocytes as expected.](http://images.novusbio.com/fullsize/Integrin-beta-2-CD18-Antibody-Immunohistochemistry-Paraffin-NBP1-88127-img0018.jpg "Immunohistochemistry-Paraffin: Integrin beta 2/CD18 Antibody [NBP1-88127] - Staining of human skeletal muscle shows no positivity in myocytes as expected.")
![Immunohistochemistry-Paraffin: Integrin beta 2/CD18 Antibody [NBP1-88127] - Staining of human lymph node shows strong membranous positivity in germinal center cells.](http://images.novusbio.com/fullsize/Integrin-beta-2-CD18-Antibody-Immunohistochemistry-Paraffin-NBP1-88127-img0019.jpg "Immunohistochemistry-Paraffin: Integrin beta 2/CD18 Antibody [NBP1-88127] - Staining of human lymph node shows strong membranous positivity in germinal center cells.")
![Immunohistochemistry-Paraffin: Integrin beta 2/CD18 Antibody [NBP1-88127] - Staining of human tonsil shows strong membranous positivity in germinal center cells.](http://images.novusbio.com/fullsize/Integrin-beta-2-CD18-Antibody-Immunohistochemistry-Paraffin-NBP1-88127-img0020.jpg "Immunohistochemistry-Paraffin: Integrin beta 2/CD18 Antibody [NBP1-88127] - Staining of human tonsil shows strong membranous positivity in germinal center cells.")
![Immunohistochemistry ICAM-1/CD54 Antibody [Unconjugated]](https://images.novusbio.com/images2/ICAM1_AF796_Immunohistochemistry_17354.jpg)
![Western Blot ICAM-1/CD54 Antibody [Unconjugated]](https://images.novusbio.com/images/af796_mouse-icam-1-cd54-affinity-purified-polyclonal-ab-4120241048112.jpg)
![Western Blot ICAM-1/CD54 Antibody [Unconjugated]](https://images.novusbio.com/images/af796_mouse-icam-1-cd54-affinity-purified-polyclonal-ab-41202410481112.jpg)
![Western Blot Integrin alpha L/CD11a Antibody (345913) [Unconjugated]](https://images.novusbio.com/images2/Integrin_alpha_L_MAB3595_Western_Blot_10266.jpg)
![Simple Western Integrin alpha L/CD11a Antibody (345913) [Unconjugated]](https://images.novusbio.com/images2/mab3595_human-integrin-alpha-l-cd11a-mab-clone-345913-simple-western-268202215744.jpg)
![SDS-PAGE TNF-alpha [Unconjugated]](https://images.novusbio.com/images2/TNF-alpha_210-TA_256.jpg)
![Bioactivity TNF-alpha [Unconjugated]](https://images.novusbio.com/images2/TNFalpha_210TA_1658.jpg)
![SEC-MALS TNF-alpha [Unconjugated]](https://images.novusbio.com/images/210-ta_recombinant-human-tnf-alpha-protein-sec-mals-35202312244..jpg)
![Bioactivity CTLA-4 [Unconjugated]](https://images.novusbio.com/images2/CTLA4_7268CT_2293.jpg)
![Bioactivity IL-2 [Unconjugated]](https://images.novusbio.com/images/202-il_recombinant-human-il-2-protein-bioactivity-174202314946.jpg)
![Bioactivity IFN-gamma [Unconjugated]](https://images.novusbio.com/images2/IFNgamma_285IF_2848.jpg)
![SDS-PAGE IFN-gamma [Unconjugated]](https://images.novusbio.com/images2/IFN-gamma_285-IF_230.jpg)
![SEC-MALS IFN-gamma [Unconjugated]](https://images.novusbio.com/images/285-if_recombinant-human-ifn-gamma-protein-sec-mals-1520239228..jpg)
![Immunocytochemistry Aminopeptidase N/CD13 Antibody [Unconjugated]](https://images.novusbio.com/images2/Aminopeptidase_N_AF2335_Immunocytochemistry__Immunofluorescence_17382.jpg)
![Immunohistochemistry Aminopeptidase N/CD13 Antibody [Unconjugated]](https://images.novusbio.com/images2/Aminopeptidase_N_AF2335_Immunohistochemistry_23316.jpg)
![Western Blot: Goat anti-Rabbit IgG (H+L) Secondary Antibody [HRP] [NB7160] - Western blot showing vemurafenib treatment in BRAFV600E CRC cells inhibits fission mediator DRP1 with no significant effect on fusion proteins (Mfn1 & 2) using MFN-1 antibody (NBP1-51841) and corresponding secondary antibody, goat anti-rabbit IgG-HRP (NB7160). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/33738242).](https://images.novusbio.com/images/Goat-anti-Rabbit-IgG-H+L-Secondary-Antibody-HRP-Western-Blot-NB7160-img0001.jpg "Western Blot: Goat anti-Rabbit IgG (H+L) Secondary Antibody [HRP] [NB7160] - Western blot showing vemurafenib treatment in BRAFV600E CRC cells inhibits fission mediator DRP1 with no significant effect on fusion proteins (Mfn1 & 2) using MFN-1 antibody (NBP1-51841) and corresponding secondary antibody, goat anti-rabbit IgG-HRP (NB7160). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/33738242).")
![Flow Cytometry: Rabbit IgG Isotype Control [NBP2-24891] - Intracellular FACS analysis of mouse TLR6 polyclonal antibody (red), rabbit isotype control (green), RAW cells alone (shaded). Two micrograms of antibodies were used. Goat anti-rabbit FITC (Novus, 20302) was used as secondary.](https://images.novusbio.com/images/Rabbit--Mouse-IgG-Isotype-Control-Flow-Cytometry-NBP2-24891-img0001.jpg "Flow Cytometry: Rabbit IgG Isotype Control [NBP2-24891] - Intracellular FACS analysis of mouse TLR6 polyclonal antibody (red), rabbit isotype control (green), RAW cells alone (shaded). Two micrograms of antibodies were used. Goat anti-rabbit FITC (Novus, 20302) was used as secondary.")