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IL-27 Antibody [DyLight 350]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 350

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-76698AF350
Alexa Fluor 405
NBP1-76698AF405
Alexa Fluor 488
NBP1-76698AF488
Alexa Fluor 532
NBP1-76698AF532
Alexa Fluor 594
NBP1-76698AF594
Alexa Fluor 647
NBP1-76698AF647
Alexa Fluor 700
NBP1-76698AF700
Alexa Fluor 750
NBP1-76698AF750
Biotin
NBP1-76698B
CoraFluor 1
NBP1-76698CL1
DyLight 405
NBP1-76698V
DyLight 488
NBP1-76698G
DyLight 550
NBP1-76698R
DyLight 594
NBP1-76698DL594
DyLight 650
NBP1-76698C
DyLight 680
NBP1-76698FR
DyLight 755
NBP1-76698IR
FITC
NBP1-76698F
HRP
NBP1-76698H
Janelia Fluor 525
NBP1-76698JF525
Janelia Fluor 549
NBP1-76698JF549
Janelia Fluor 646
NBP1-76698JF646
Janelia Fluor 669
NBP1-76698JF669
PerCP
NBP1-76698PCP
Unconjugated
NBP1-76698
mFluor Violet 450 SE
NBP1-76698MFV450
mFluor Violet 500 SE
NBP1-76698MFV500
mFluor Violet 610 SE
NBP1-76698MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-76698
BSA Free
NBP1-76698
BSA Free
NBP1-76698-0.025mg
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IL-27 Antibody [DyLight 350] Summary

Immunogen
Antibody was raised against a peptide corresponding to 16 amino acids near the amino terminus of human IL-27. The immunogen is located within the first 50 amino acids of IL-27. Amino Acid Squence: WGFPRPPGRPQLSLQE
Specificity
Human IL-27 has one isoform (243aa, 28kD). Mouse IL-27 has one isoform (234aa, 27kD) and rat IL-27 also has one isoform (234aa, 27kD). NBP1-76698 can detect human, mouse and rat IL-27.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
IL27
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for IL-27 Antibody [DyLight 350]

  • IL-27 p28 subunit
  • IL-27 subunit alpha
  • IL27
  • IL-27
  • IL27A
  • IL-27-A
  • IL27-A
  • IL27p28
  • IL30
  • interleukin 27
  • interleukin 30
  • interleukin-27 subunit alpha
  • MGC71873
  • p28IL-27A

Background

IL27 is encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol IL27