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IkB-alpha [p Ser36] Antibody (39A1413) [DyLight 594]

 
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Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, CaSpecies Glossary
Applications WB, Simple Western, IP
Clone
39A1413
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 594

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-56724AF350
Alexa Fluor 405
NB100-56724AF405
Alexa Fluor 488
NB100-56724AF488
Alexa Fluor 532
NB100-56724AF532
Alexa Fluor 594
NB100-56724AF594
Alexa Fluor 647
NB100-56724AF647
Alexa Fluor 700
NB100-56724AF700
Alexa Fluor 750
NB100-56724AF750
Biotin
NB100-56065
Biotin
NB100-56724B
DyLight 350
NB100-56724UV
DyLight 405
NB100-56724V
DyLight 488
NB100-56724G
DyLight 550
NB100-56724R
DyLight 650
NB100-56724C
DyLight 680
NB100-56724FR
DyLight 755
NB100-56724IR
FITC
NB100-56724F
HRP
NB100-56724H
Janelia Fluor 549
NB100-56724JF549
Janelia Fluor 646
NB100-56724JF646
Unconjugated
NB100-56724
mFluor Violet 450 SE
NB100-56724MFV450
mFluor Violet 500 SE
NB100-56724MFV500
mFluor Violet 610 SE
NB100-56724MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB100-56724
BSA Free
NB100-56724SS
Azide Free
NBP2-33247
BSA Free
NB100-56724
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IkB-alpha [p Ser36] Antibody (39A1413) [DyLight 594] Summary

Immunogen
This monoclonal antibody was raised against a synthetic peptide containing phosphorylated serines at amino acid residues 32 and 36 of human IkBa.
Modification
p Ser36
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
NFKBIA
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation
  • Simple Western
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for IkB-alpha [p Ser36] Antibody (39A1413) [DyLight 594]

  • alpha
  • I-kappa-B-alpha
  • IkappaBalphaNF-kappa-B inhibitor alpha
  • IKBAikB-alpha
  • IkBalpha
  • IkB-alpha
  • MAD3
  • MAD-3
  • Major histocompatibility complex enhancer-binding protein MAD3
  • NFKBI
  • NFKBIA
  • nuclear factor of kappa light chain gene enhancer in B-cells
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor

Background

NF-kB is silenced in the cytoplasm by an inhibitory protein, IkB (1). Synthesis of IkBa is autoregulated (2). IkB proteins are phosphorylated by IkB kinase complex consisting of at least three proteins, IKK1/a, IKK2/b, and IKK3/g (3-6). External stimuli such as tumor necrosis factor or other cytokines results in phosphorylation and degradation of IkB releasing NF-kB dimers. NF-kB dimer subsequently translocates to the nucleus and activates target genes. Six members of IkB family members have been identified (1). One of the first gene induced following NF-kB activation is IkBa.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol NFKBIA