hnRNP H Antibody

The heterogeneous nuclear Ribonucleoprotein (hnRNP) H protein family is involved in pre-mRNA processing. It is essential for enhancer activity. The sequence GGGA is recognized by all hnRNP H family proteins. Mutant exon 6D sequences function as a splicing enhancer when inserted into an enhancer-dependent splicing construct. hnRNP H family proteins bind to the enhancer and their binding is dependent on the sequence GGGA, located just downstream of the point of mutation.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: WB.

Showing Publications 1 - 10 of 16. Show All 16 Publications. Collapse Publications.

Publications using NB100-385	Applications	Species
Bajc Cesnik A, Darovic S, Prpar Mihevc S et al. Nuclear RNA foci from C9ORF72 expansion mutation form paraspeckle-like bodies J. Cell. Sci. 2019-02-11 [PMID: 30745340]
Li Y, Bakke J, Finkelstein D et al. HNRNPH1 is required for rhabdomyosarcoma cell growth and survival Oncogenesis 2018-01-24 [PMID: 29362363] (WB, Human)	WB	Human
Kieffer-Kwon P, Happel C, Uldrick TS et al. KSHV MicroRNAs Repress Tropomyosin 1 and Increase Anchorage-Independent Growth and Endothelial Tube Formation. PLoS ONE. 2015-08-12 [PMID: 26263384] (WB, Human)	WB	Human
Lee KY, Li M, Manchanda M et al. Compound loss of muscleblind-like function in myotonic dystrophy. EMBO Mol Med. 2013-12-01 [PMID: 24293317] (WB, Mouse)	WB	Mouse
Vivarelli S, Lenzken SC, Ruepp MD et al. Paraquat Modulates Alternative Pre-mRNA Splicing by Modifying the Intracellular Distribution of SRPK2. PLoS One 2013-04-16 [PMID: 23613995] (WB, Human)	WB	Human
Wang E, Mueller WF, Hertel KJ et al. G Run-mediated recognition of proteolipid protein and DM20 5' splice sites by U1 small nuclear RNA is regulated by context and proximity to the splice site. J Biol Chem 2011-02-01 [PMID: 21127064]
Ling SC, Albuquerque CP, Han JS et al. ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS. Proc Natl Acad Sci U S A. 2010-07-12 [PMID: 20624952]
Van Dusen CM, Yee L, McNally LM et al. A glycine-rich domain of hnRNP H/F promotes nucleocytoplasmic shuttling and nuclear import through an interaction with transportin 1. Mol Cell Biol 2010-05-01 [PMID: 20308327]
Ohe K, Watanabe T, Harada S et al. Regulation of alternative splicing of the receptor for advanced glycation endproducts (RAGE) through G-rich cis-elements and heterogenous nuclear ribonucleoprotein H. J Biochem 2010-05-01 [PMID: 20028692]
de Planell-Saguer M, Schroeder DG, Rodicio MC et al. Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery. Hum Mol Genet 2009-06-01 [PMID: 19299493]
Wang E, Cambi F. Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs. J Biol Chem 2009-04-01 [PMID: 19244236]
Jonson L, Vikesaa J, Krogh A et al. Molecular composition of IMP1 ribonucleoprotein granules. Mol Cell Proteomics 2007-05-01 [PMID: 17289661]
Cathelin S, Rebe C, Haddaoui L et al. Identification of proteins cleaved downstream of caspase activation in monocytes undergoing macrophage differentiation. J Biol Chem 2006-06-01 [PMID: 16636047]
Zhang D, Tai YC, Wong CH et al. Molecular response of leukemia HL-60 cells to genistein treatment, a proteomics study. Leuk Res 2007-01-01 [PMID: 16616778]
McNally LM, Yee L, McNally MT et al. Heterogeneous nuclear ribonucleoprotein H is required for optimal U11 small nuclear ribonucleoprotein binding to a retroviral RNA-processing control element: implications for U12-dependent RNA splicing. J Biol Chem 2006-02-01 [PMID: 16308319]
Rauch J, Ahlemann M, Schaffrik M et al. Allogenic antibody-mediated identification of head and neck cancer antigens. Biochem Biophys Res Commun 2004-10-01 [PMID: 15351715]
Show All 16 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
Enlarge	3 reviewed by: Simona Darovic	IF	Human	01/21/2015	View Summary Application Immunofluorescence Sample Tested SH-SY5Y cell culture Species Human Lot A2

Array NB100-385

• hnRNP H Antibodies
• hnRNP H Lysate