CFTR Antibody (24-1) [Unconjugated] - C-terminus

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Cystic fibrosis transmembrane conductance regulator (CFTR) is a multi-pass transmembrane protein that functions as a chloride channel. CFTR belongs to the ATP‑binding cassette (ABC) superfamily. Mutations in CFTR cause the pulmonary disease, cystic fibrosis (CF). Specifically, deletion of phenyalanine at position 508 (DeltaF508-CFTR) results in a folding defect which impairs chloride channel function. The mechanism by which channel dysfunction relates to disease symptoms is a focus of intense research. CFTR dysfunction results in disruption of ion transport and subsequent blockage of airways by secreted mucus. CFTR may also play a role in the skeletal muscle atrophy and dysfunction that characterizes CF. In addition, CFTR-mediated chloride secretion underlies fluid accumulation and cyst growth in autosomal dominant polycystic kidney disease (ADPKD).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 11 confirmed species: Human, Mouse, Rat, Amphibian, Fish, Fish - Goldline seabream, Fish - Plotosus lineatus (Striped Eel Catfish), Ovine, Primate - Cercopithecus aethiops (African Green Monkey), Primate - Chlorocebus pygerythrus (Vervet Monkey), Xenopus.

We have publications tested in 8 applications: Co-Immunoprecipitation, Flow Cytometry, ICC, IHC, IHC-Fr, IHC-P, Immunoprecipitation, Western Blot.

Showing Publications 1 - 10 of 76. Show All 76 Publications. Collapse Publications.

Publications using MAB25031	Applications	Species
Caohuy, H;Eidelman, O;Chen, T;Mungunsukh, O;Yang, Q;Walton, NI;Pollard, BS;Khanal, S;Hentschel, S;Florez, C;Herbert, AS;Pollard, HB; Inflammation in the COVID-19 airway is due to inhibition of CFTR signaling by the SARS-CoV-2 spike protein Scientific reports 2024-07-23 [PMID: 39043712] (Western Blot, Primate - Cercopithecus aethiops (African Green Monkey))	Western Blot	Primate - Cercopithecus aethiops (African Green Monkey)
Li, C;Liu, Z;Anderson, J;Liu, Z;Tang, L;Li, Y;Peng, N;Chen, J;Liu, X;Fu, L;Townes, TM;Rowe, SM;Bedwell, DM;Guimbellot, J;Zhao, R; Prime editing-mediated correction of the CFTR W1282X mutation in iPSCs and derived airway epithelial cells PloS one 2023-11-29 [PMID: 38019847] (ICC, Human)	ICC	Human
Qin-Tong Hou, Xiao-Liang Xu, Jian-Wen Wang, Xiao-Liang Dai, Li Wang, Cong-Ling Jiang et al. Loss-of-function CFTR p.G970D missense mutation might cause congenital bilateral absence of the vas deferens and be associated with impaired spermatogenesis Asian Journal of Andrology 2023-01-01 [PMID: 35665694]
Nathaniel J. Henning, Lydia Boike, Jessica N. Spradlin, Carl C. Ward, Gang Liu, Erika Zhang et al. Deubiquitinase-targeting chimeras for targeted protein stabilization Nature Chemical Biology 2022-04-01 [PMID: 35210618]
SM Snow, KA Matkowskyj, M Maresh, L Clipson, TN Vo, KA Johnson, DA Deming, MA Newton, WM Grady, PJ Pickhardt, RB Halberg Validation of genetic classifiers derived from mouse and human tumors to identify molecular subtypes of colorectal cancer Human pathology, 2021-10-14;0(0):. 2021-10-14 [PMID: 34655611] (IHC, Human)	IHC	Human
P Kumar, DK Soni, C Sen, MB Larsen, K Mazan-Mamc, Y Piao, S De, M Gorospe, RA Frizzell, R Biswas SFPQ rescues F508del-CFTR expression and function in cystic fibrosis bronchial epithelial cells Scientific Reports, 2021-08-17;11(1):16645. 2021-08-17 [PMID: 34404863] (IHC, Human)	IHC	Human
Chun Chih Chen, William S. Marshall, George N. Robertson, Regina R. F. Cozzi, Scott P. Kelly Mummichog gill and operculum exhibit functionally consistent claudin-10 paralog profiles and Claudin-10c hypersaline response Biology Open 2021-07-15 [PMID: 34308991]
M Badaoui, A Zoso, T Idris, M Bacchetta, J Simonin, S Lemeille, B Wehrle-Hal, M Chanson Vav3 Mediates Pseudomonas aeruginosa Adhesion to the Cystic Fibrosis Airway Epithelium Cell Rep, 2020-07-07;32(1):107842. 2020-07-07 [PMID: 32640241] (ICC, Human)	ICC	Human
Ilan M. Ruhr, Chris M. Wood, Kevin L. Schauer, Yadong Wang, Edward M. Mager, Bruce Stanton et al. Is aquaporin‐3 involved in water‐permeability changes in the killifish during hypoxia and normoxic recovery, in freshwater or seawater? Journal of Experimental Zoology Part A: Ecological and Integrative Physiology 2020-08-01 [PMID: 32548921]
Rehman T, Thornell IM, Pezzulo AA et al. TNFalpha and IL-17 Alkalinize Airway Surface Liquid through CFTR and Pendrin Am. J. Physiol., Cell Physiol. 5/20/2020 [PMID: 32432926]
M Favia, C Gallo, L Guerra, D De Venuto, A Diana, AM Polizzi, P Montemurro, MA Mariggiò, G Leonetti, A Manca, V Casavola, M Conese Treatment of Cystic Fibrosis Patients Homozygous for F508del with Lumacaftor-Ivacaftor (Orkambi�) Restores Defective CFTR Channel Function in Circulating Mononuclear Cells Int J Mol Sci, 2020-03-31;21(7):. 2020-03-31 [PMID: 32244302] (Western Blot, Human)	Western Blot	Human
G Ortiz-Muno, MA Yu, E Lefrançais, B Mallavia, C Valet, JJ Tian, S Ranucci, KM Wang, Z Liu, N Kwaan, D Dawson, ME Kleinhenz, FT Khasawneh, PM Haggie, AS Verkman, MR Looney Cystic fibrosis transmembrane conductance regulator dysfunction in platelets drives lung hyperinflammation J. Clin. Invest., 2020-04-01;0(0):. 2020-04-01 [PMID: 31961827] (Western Blot, Human)	Western Blot	Human
DC Borcherdin, ME Siefert, S Lin, J Brewington, H Sadek, JP Clancy, SM Plafker, AG Ziady Clinically-approved CFTR modulators rescue Nrf2 dysfunction in cystic fibrosis airway epithelia J. Clin. Invest., 2019-05-30;130(0):. 2019-05-30 [PMID: 31145101] (Co-Immunoprecipitation, Human)	Co-Immunoprecipitation	Human
Marozkina N, Bosch J, Cotton C et al. Cyclic compression increases F508 Del CFTR expression in ciliated human airway epithelium American Journal of Physiology-Lung Cellular and Molecular Physiology 2019-08-01 [PMID: 31116581]
Zeljka Trepotec, Johannes Geiger, Christian Plank, Manish K. Aneja, Carsten Rudolph Segmented poly(A) tails significantly reduce recombination of plasmid DNA without affecting mRNA translation efficiency or half-life RNA 2019-04-01 [PMID: 30647100]
Emily Xia, Yiqian Zhang, Huibi Cao, Jun Li, Rongqi Duan, Jim Hu TALEN-Mediated Gene Targeting for Cystic Fibrosis-Gene Therapy Genes (Basel) 2019-01-11 [PMID: 30641980]
S Malakpour, J Coimbra, JM Wilson Effect of dendritic organ ligation on striped eel catfish Plotosus lineatus osmoregulation PLoS ONE, 2018-10-23;13(10):e0206206. 2018-10-23 [PMID: 30352080] (IHC-P, Fish - Plotosus lineatus (Striped Eel Catfish))	IHC-P	Fish - Plotosus lineatus (Striped Eel Catfish)
D De Rocco, B Pompili, S Castellani, E Morini, L Cavinato, G Cimino, MA Mariggiò, S Guarnieri, M Conese, P Del Porto, F Ascenzioni Assembly and Functional Analysis of an S/MAR Based Episome with the Cystic Fibrosis Transmembrane Conductance Regulator Gene Int J Mol Sci, 2018-04-17;19(4):. 2018-04-17 [PMID: 29673202] (ICC, Western Blot, Human)	ICC, Western Blot	Human
Annalucia Carbone, Roberto Zefferino, Elisa Beccia, Valeria Casavola, Stefano Castellani, Sante Di Gioia et al. Gap Junctions Are Involved in the Rescue of CFTR-Dependent Chloride Efflux by Amniotic Mesenchymal Stem Cells in Coculture with Cystic Fibrosis CFBE41o- Cells Stem Cells International 2018-01-11 [PMID: 29531530]
Ilan M. Ruhr, Kevin L. Schauer, Yoshio Takei, Martin Grosell Renoguanylin stimulates apical CFTR translocation and decreases HCO3− secretion through PKA activity in the Gulf toadfish (Opsanus beta) Journal of Experimental Biology 2018-01-01 [PMID: 29361605]
A Schögler, F Blank, M Brügger, S Beyeler, SA Tschanz, N Regamey, C Casaulta, T Geiser, MP Alves Characterization of pediatric cystic fibrosis airway epithelial cell cultures at the air-liquid interface obtained by non-invasive nasal cytology brush sampling Respir. Res., 2017-12-28;18(1):215. 2017-12-28 [PMID: 29282053] (ICC, Human)	ICC	Human
Marty Kwok Shing Wong, Takehiro Tsukada, Nobuhiro Ogawa, Supriya Pipil, Haruka Ozaki, Yutaka Suzuki et al. A sodium binding system alleviates acute salt stress during seawater acclimation in eels Zoological Letters 2017-12-12 [PMID: 29255617]
CL Shrestha, KD Assani, H Rinehardt, F Albastroiu, S Zhang, R Shell, AO Amer, LS Schlesinge, BT Kopp Cysteamine-mediated clearance of antibiotic-resistant pathogens in human cystic fibrosis macrophages PLoS ONE, 2017-10-05;12(10):e0186169. 2017-10-05 [PMID: 28982193] (Western Blot, Human)	Western Blot	Human
K Arora, Y Huang, K Mun, S Yarlagadda, N Sundaram, MM Kessler, G Hannig, CB Kurtz, I Silos-Sant, M Helmrath, JJ Palermo, JP Clancy, KA Steinbrech, AP Naren Guanylate cyclase 2C agonism corrects CFTR mutants JCI Insight, 2017-10-05;2(19):. 10/5/2017 [PMID: 28978796]
Roberto Plebani, Romina Tripaldi, Paola Lanuti, Antonio Recchiuti, Sara Patruno, Sara Di Silvestre et al. Establishment and long-term culture of human cystic fibrosis endothelial cells Laboratory Investigation 2017-11-01 [PMID: 28759010]
MF Figueira, RC Castiglion, CM de Lemos B, FM Ornellas, G da Silva F, MM Morales, RN da Fonseca, J de Souza-M Diabetic rats present higher urinary loss of proteins and lower renal expression of megalin, cubilin, ClC-5, and CFTR Physiol Rep, 2017-07-01;5(13):. 2017-07-01 [PMID: 28676554] (Western Blot, Rat)	Western Blot	Rat
XL Chen, B Zhang, YR Chng, JLY Ong, SF Chew, WP Wong, SH Lam, T Nakada, YK Ip Ammonia exposure affects the mRNA and protein expression levels of certain Rhesus glycoproteins in the gills of climbing perch J. Exp. Biol., 2017-06-02;0(0):. 2017-06-02 [PMID: 28576822] (IHC-P, Fish)	IHC-P	Fish
W. S. Marshall, R. R. F. Cozzi, M. Spieker WNK1 and p38-MAPK distribution in ionocytes and accessory cells of euryhaline teleost fish implies ionoregulatory function Biology Open 2017-07-15 [PMID: 28522431]
Z Bozoky, S Ahmadi, T Milman, TH Kim, K Du, M Di Paola, S Pasyk, R Pekhletski, JP Keller, CE Bear, JD Forman-Kay Synergy of cAMP and calcium signaling pathways in CFTR regulation Proc. Natl. Acad. Sci. U.S.A, 2017-02-27;0(0):. 2017-02-27 [PMID: 28242698] (Human)		Human
Israel Hanukoglu, Vijay R. Boggula, Hananya Vaknine, Sachin Sharma, Thomas Kleyman, Aaron Hanukoglu Expression of epithelial sodium channel (ENaC) and CFTR in the human epidermis and epidermal appendages Histochemistry and Cell Biology 2017-06-01 [PMID: 28130590]
Deep interactome profiling of membrane proteins by co-interacting protein identification technology Nat Protoc, 2016-11-17;11(12):2515-2528. 2016-11-17 [PMID: 27854364] (Immunoprecipitation, Human)	Immunoprecipitation	Human
Agathe Tarze New use for an old drug: COX-independent anti-inflammatory effects of sulindac in models of cystic fibrosis Br. J. Pharmacol., 2016-04-21;173(11):1728-41. 2016-04-21 [PMID: 26894321] (Western Blot, Human)	Western Blot	Human
Anna C. Abbattiscianni, Maria Favia, Maria T. Mancini, Rosa A. Cardone, Lorenzo Guerra, Stefania Monterisi et al. Correctors of mutant CFTR enhance subcortical cAMP-PKA signaling through modulating ezrin phosphorylation and cytoskeleton organization Journal of Cell Science 2016-03-15 [PMID: 26823603]
Jessica Bellec, Marc Bacchetta, Davide Losa, Ignacio Anegon, Marc Chanson, Tuan Huy Nguyen <i>CFTR</i> Inactivation by Lentiviral Vector-mediated RNA Interference and CRISPR-Cas9 Genome Editing in Human Airway Epithelial Cells Current Gene Therapy 2015-08-25 [PMID: 26264708]
Barbara Dhooghe, Charlotte Bouckaert, Arnaud Capron, Pierre Wallemacq, Teresinha Leal, Sabrina Noel Resveratrol increases F508del-CFTR dependent salivary secretion in cystic fibrosis mice Biology Open 2015-07-15 [PMID: 26092868]
Fumiya Furukawa, Soichi Watanabe, Andre P. Seale, Jason P. Breves, Darren T. Lerner, E Gordon Gordon Grau et al. In vivo and in vitro effects of high-K(+) stress on branchial expression of ROMKa in seawater-acclimated Mozambique tilapia Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 2015-09-01 [PMID: 26021981]
Tabeling C, Yu H, Wang L, Ranke H, Goldenberg N, Zabini D, Noe E, Krauszman A, Gutbier B, Yin J, Schaefer M, Arenz C, Hocke A, Suttorp N, Proia R, Witzenrath M, Kuebler W CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction. Proc Natl Acad Sci U S A, 2015-03-17;112(13):E1614-23. 2015-03-17 [PMID: 25829545] (Immunoprecipitation, Western Blot, Mouse)	Immunoprecipitation, Western Blot	Mouse
Ferru-Clement R, Fresquet F, Norez C, Metaye T, Becq F, Kitzis A, Thoreau V Involvement of the Cdc42 pathway in CFTR post-translational turnover and in its plasma membrane stability in airway epithelial cells. PLoS ONE, 2015-03-13;10(3):e0118943. 2015-03-13 [PMID: 25768293] (Western Blot, Human)	Western Blot	Human
Caohuy H, Yang Q, Eudy Y, Ha T, Xu A, Glover M, Frizzell R, Jozwik C, Pollard H Activation of 3-phosphoinositide-dependent kinase 1 (PDK1) and serum- and glucocorticoid-induced protein kinase 1 (SGK1) by short-chain sphingolipid C4-ceramide rescues the trafficking defect of DeltaF508-cystic fibrosis transmembrane conductance regulator (DeltaF508-CFTR). J Biol Chem, 2014-11-10;289(52):35953-68. 2014-11-10 [PMID: 25384981] (ICC, Immunoprecipitation, Western Blot, Human)	ICC, Immunoprecipitation, Western Blot	Human
Runzhen Zhao, Xinrong Liang, Meimi Zhao, Shan-Lu Liu, Yao Huang, Steven Idell et al. Correlation of Apical Fluid-Regulating Channel Proteins with Lung Function in Human COPD Lungs PLoS ONE 2014-10-17 [PMID: 25329998]
Pascale Marcorelles, Gaëlle Friocourt, Arnaud Uguen, Françoise Ledé, Claude Férec, Annie Laquerrière Cystic fibrosis transmembrane conductance regulator protein (CFTR) expression in the developing human brain: comparative immunohistochemical study between patients with normal and mutated CFTR Journal of Histochemistry & Cytochemistry 2014-11-01 [PMID: 25062999]
Hassan F, Xu X, Nuovo G, Killilea D, Tyrrell J, Da Tan C, Tarran R, Diaz P, Jee J, Knoell D, Boyaka P, Cormet-Boyaka E Accumulation of metals in GOLD4 COPD lungs is associated with decreased CFTR levels. Respir Res, 2014-06-23;15(0):69. 2014-06-23 [PMID: 24957904] (Western Blot, Human)	Western Blot	Human
Carbone A, Castellani S, Favia M, Diana A, Paracchini V, Di Gioia S, Seia M, Casavola V, Colombo C, Conese M Correction of defective CFTR/ENaC function and tightness of cystic fibrosis airway epithelium by amniotic mesenchymal stromal (stem) cells. J Cell Mol Med, 2014-06-03;18(8):1631-43. 2014-06-03 [PMID: 24894806] (Flow Cytometry, Western Blot, Human)	Flow Cytometry, Western Blot	Human
Maria Favia, Maria T. Mancini, Valentino Bezzerri, Lorenzo Guerra, Onofrio Laselva, Anna C. Abbattiscianni et al. Trimethylangelicin promotes the functional rescue of mutant F508del CFTR protein in cystic fibrosis airway cells American Journal of Physiology-Lung Cellular and Molecular Physiology 2014-07-01 [PMID: 24816489]
Losa D, Kohler T, Bellec J, Dudez T, Crespin S, Bacchetta M, Boulanger P, Hong S, Morel S, Nguyen T, van Delden C, Chanson M Pseudomonas aeruginosa-induced apoptosis in airway epithelial cells is mediated by gap junctional communication in a JNK-dependent manner. J Immunol, 2014-04-14;192(10):4804-12. 2014-04-14 [PMID: 24733844] (Western Blot, Human)	Western Blot	Human
Li Z, Lui E, Wilson J, Ip Y, Lin Q, Lam T, Lam S Expression of key ion transporters in the gill and esophageal-gastrointestinal tract of euryhaline Mozambique tilapia Oreochromis mossambicus acclimated to fresh water, seawater and hypersaline water. PLoS ONE, 2014-01-31;9(1):e87591. 2014-01-31 [PMID: 24498146] (IHC-P, Fish)	IHC-P	Fish
Cebotaru L, Rapino D, Cebotaru V, Guggino W Correcting the cystic fibrosis disease mutant, A455E CFTR. PLoS ONE, 2014-01-08;9(1):e85183. 2014-01-08 [PMID: 24416359] (Western Blot, Primate - Chlorocebus pygerythrus (Vervet Monkey))	Western Blot	Primate - Chlorocebus pygerythrus (Vervet Monkey)
Barbara Dhooghe, Sabrina Noël, Caroline Bouzin, Gaëtane Behets-Wydemans, Teresinha Leal Correction of Chloride Transport and Mislocalization of CFTR Protein by Vardenafil in the Gastrointestinal Tract of Cystic Fibrosis Mice PLoS ONE 2013-10-24 [PMID: 24204804]
El Khouri E, Le Pavec G, Toledano M, Delaunay-Moisan A RNF185 is a novel E3 ligase of endoplasmic reticulum-associated degradation (ERAD) that targets cystic fibrosis transmembrane conductance regulator (CFTR). J Biol Chem, 2013-09-09;288(43):31177-91. 2013-09-09 [PMID: 24019521] (Immunoprecipitation, Human)	Immunoprecipitation	Human
Viart V, Varilh J, Lopez E, Rene C, Claustres M, Taulan-Cadars M Phosphorylated C/EBPbeta influences a complex network involving YY1 and USF2 in lung epithelial cells. PLoS ONE, 2013-04-01;8(4):e60211. 2013-04-01 [PMID: 23560079] (Immunoprecipitation, Human)	Immunoprecipitation	Human
Oglesby I, Chotirmall S, McElvaney N, Greene C Regulation of cystic fibrosis transmembrane conductance regulator by microRNA-145, -223, and -494 is altered in DeltaF508 cystic fibrosis airway epithelium. J Immunol, 2013-02-22;190(7):3354-62. 2013-02-22 [PMID: 23436935] (Western Blot, Human)	Western Blot	Human
Duan , Yuanyuan, Sun , Ying, Zhang , Fan, Zhang , Wei Kevi, Wang , Dong, Wang , Yan, Cao , Xu, Hu , Wenbao, Xie , Changyan, Cuppoletti , John, Magin , Thomas M, Wang , Haixia, Wu , Zhenguo, Li , Ning, Huang , Pingbo Keratin K18 increases cystic fibrosis transmembrane conductance regulator (CFTR) surface expression by binding to its C-terminal hydrophobic patch. J Biol Chem, 2012-10-08;287(48):40547-59. 2012-10-08 [PMID: 23045527] (Immunoprecipitation, Human)	Immunoprecipitation	Human
Murphy , Sean V, Lim , Rebecca, Heraud , Philip, Cholewa , Marian, Le Gros , Mark, de Jonge , Martin D, Howard , Daryl L, Paterson , David, McDonald , Courtney, Atala , Anthony, Jenkin , Graham, Wallace , Euan M Human amnion epithelial cells induced to express functional cystic fibrosis transmembrane conductance regulator. PLoS ONE, 2012-09-28;7(9):e46533. 2012-09-28 [PMID: 23029546] (Flow Cytometry, ICC, Western Blot, Human)	Flow Cytometry, ICC, Western Blot	Human
King , J Darwin, Lee , Jeffrey, Riemen , Claudia, Neumann , Dietbert, Xiong , Sheng, Foskett , J Kevin, Mehta , Anil, Muimo , Richmond, Hallows , Kenneth Role of binding and nucleoside diphosphate kinase A in the regulation of the cystic fibrosis transmembrane conductance regulator by AMP-activated protein kinase. J Biol Chem, 2012-08-06;287(40):33389-400. 2012-08-06 [PMID: 22869372] (Immunoprecipitation, Western Blot, Human)	Immunoprecipitation, Western Blot	Human
Teng L, Kerbiriou M, Taiya M, Le Hir S, Mignen O, Benz N, Trouve P, Ferec C Proteomic Identification of Calumenin as a G551D - CFTR Associated Protein. PLoS ONE, 2012-06-29;7(6):e40173. 2012-06-29 [PMID: 22768251] (Western Blot, Human)	Western Blot	Human
Valentina Paracchini, Annalucia Carbone, Federico Colombo, Stefano Castellani, Silvia Mazzucchelli, Sante Di Di Gioia et al. Amniotic Mesenchymal Stem Cells: A New Source for Hepatocyte-Like Cells and Induction of CFTR Expression by Coculture with Cystic Fibrosis Airway Epithelial Cells Journal of Biomedicine and Biotechnology 2012-01-22 [PMID: 22315512]
Sorio C, Buffelli M, Angiari C, Ettorre M, Johansson J, Vezzalini M, Viviani L, Ricciardi M, Verze G, Assael BM, Melotti P Defective CFTR expression and function are detectable in blood monocytes: development of a new blood test for cystic fibrosis. PLoS ONE, 2011-07-21;6(7):e22212. 2011-07-21 [PMID: 21811577] (Western Blot, Human)	Western Blot	Human
Donatella Piro, Claudia Piccoli, Lorenzo Guerra, Francesca Sassone, Annamaria D'Aprile, Maria Favia et al. Hematopoietic Stem/Progenitor Cells Express Functional Mitochondrial Energy-Dependent Cystic Fibrosis Transmembrane Conductance Regulator Stem Cells and Development 2012-03-01 [PMID: 21561312]
Drevillon L, Tanguy G, Hinzpeter A et al. COMMD1-Mediated Ubiquitination Regulates CFTR Trafficking. PLoS One. 3/31/2011 [PMID: 21483833]
Jean-Marie Zahm, Franck Delavoie, Férial Toumi, Béatrice Nawrocki-Raby, Claire Kileztky, Jean Michel et al. Long acting beta2-agonist and corticosteroid restore airway glandular cell function altered by bacterial supernatant Respiratory Research 2010-12-01 [PMID: 20089165]
Antonius Bronckers, Lida Kalogeraki, Huub J.N. Jorna, Martina Wilke, Theodore J. Bervoets, Donacian M. Lyaruu et al. The cystic fibrosis transmembrane conductance regulator (CFTR) is expressed in maturation stage ameloblasts, odontoblasts and bone cells Bone 2010-04-01 [PMID: 20004757]
D. J. McKeon, K. A. Cadwallader, S. Idris, A. S. Cowburn, M. C. Pasteur, H. Barker et al. Cystic fibrosis neutrophils have normal intrinsic reactive oxygen species generation European Respiratory Journal 2010-06-01 [PMID: 19840964]
Fouassier L, Rosenberg P, Mergey M, Saubamea B, Claperon A, Kinnman N, Chignard N, Jacobsson-Ekman G, Strandvik B, Rey C, Barbu V, Hultcrantz R, Housset C Ezrin-radixin-moesin-binding phosphoprotein (EBP50), an estrogen-inducible scaffold protein, contributes to biliary epithelial cell proliferation. Am. J. Pathol., 2009-03-01;174(3):869-80. 2009-03-01 [PMID: 19234136] (IHC, Human)	IHC	Human
Cebotaru L, Vij N, Ciobanu I, Wright J, Flotte T, Guggino WB Cystic fibrosis transmembrane regulator missing the first four transmembrane segments increases wild type and DeltaF508 processing. J. Biol. Chem., 2008-05-28;283(32):21926-33. 2008-05-28 [PMID: 18508776] (Western Blot, Human)	Western Blot	Human
Shead EF, Haworth CS, Condliffe AM, McKeon DJ, Scott MA, Compston JE Cystic fibrosis transmembrane conductance regulator (CFTR) is expressed in human bone. Thorax, 2007-07-01;62(7):650-1. 2007-07-01 [PMID: 17600296] (ICC, IHC, Western Blot, Human)	ICC, IHC, Western Blot	Human
Robert R, Savineau JP, Norez C, Becq F, Guibert C Expression and function of cystic fibrosis transmembrane conductance regulator in rat intrapulmonary arteries. Eur. Respir. J., 2007-06-27;30(5):857-64. 2007-06-27 [PMID: 17596272] (ICC, Immunoprecipitation, Rat)	ICC, Immunoprecipitation	Rat
Madsen SS, Jensen LN, Tipsmark CK, Kiilerich P, Borski RJ Differential regulation of cystic fibrosis transmembrane conductance regulator and Na+,K+ -ATPase in gills of striped bass, Morone saxatilis: effect of salinity and hormones. J. Endocrinol., 2007-01-01;192(1):249-60. 2007-01-01 [PMID: 17210762] (IHC-P, Western Blot, Fish)	IHC-P, Western Blot	Fish
Tang JY, Au DW The ichthyotoxic alga Chattonella marina induces Na+, K+ -ATPase, and CFTR proteins expression in fish gill chloride cells in vivo. Biochem. Biophys. Res. Commun., 2006-12-04;353(1):98-103. 2006-12-04 [PMID: 17161378] (ICC, Western Blot, Fish - Goldline seabream)	ICC, Western Blot	Fish - Goldline seabream
Painter RG, Valentine VG, Lanson NA, Leidal K, Zhang Q, Lombard G, Thompson C, Viswanathan A, Nauseef WM, Wang G CFTR Expression in human neutrophils and the phagolysosomal chlorination defect in cystic fibrosis. Biochemistry, 2006-08-29;45(34):10260-9. 2006-08-29 [PMID: 16922501] (ICC, Western Blot, Human)	ICC, Western Blot	Human
Nanua S, Sajjan U, Keshavjee S, Hershenson MB Absence of typical unfolded protein response in primary cultured cystic fibrosis airway epithelial cells. Biochem. Biophys. Res. Commun., 2006-03-03;343(1):135-43. 2006-03-03 [PMID: 16530168] (ICC, Western Blot, Human)	ICC, Western Blot	Human
Davidson H, McLachlan G, Wilson A, Boyd AC, Doherty A, MacGregor G, Davies L, Painter HA, Coles R, Hyde SC, Gill DR, Amaral MD, Collie DD, Porteous DJ, Penque D Human-specific cystic fibrosis transmembrane conductance regulator antibodies detect in vivo gene transfer to ovine airways. Am. J. Respir. Cell Mol. Biol., 2006-02-23;35(1):72-83. 2006-02-23 [PMID: 16498081] (IHC-Fr, Ovine)	IHC-Fr	Ovine
Clain J, Lehmann-Che J, Dugueperoux I, Arous N, Girodon E, Legendre M, Goossens M, Edelman A, de Braekeleer M, Teulon J, Fanen P Misprocessing of the CFTR protein leads to mild cystic fibrosis phenotype. Hum. Mutat., 2005-04-01;25(4):360-71. 2005-04-01 [PMID: 15776432] (ICC, Immunoprecipitation, Human)	ICC, Immunoprecipitation	Human
Bilan F, Thoreau V, Nacfer M, Derand R, Norez C, Cantereau A, Garcia M, Becq F, Kitzis A Syntaxin 8 impairs trafficking of cystic fibrosis transmembrane conductance regulator (CFTR) and inhibits its channel activity. J. Cell. Sci., 2004-03-23;117(0):1923-35. 2004-03-23 [PMID: 15039462] (Immunoprecipitation, Human)	Immunoprecipitation	Human
Willumsen NJ, Amstrup J, Mobjerg N, Jespersen A, Kristensen P, Larsen EH Mitochondria-rich cells as experimental model in studies of epithelial chloride channels. Biochim. Biophys. Acta, 2002-11-13;1566(1):28-43. 2002-11-13 [PMID: 12421535] (IHC-P, Xenopus)	IHC-P	Xenopus
Pan J, Bear C, Farragher S, Cutz E, Yeger H Cystic fibrosis transmembrane conductance regulator modulates neurosecretory function in pulmonary neuroendocrine cell-related tumor cell line models. Am. J. Respir. Cell Mol. Biol., 2002-11-01;27(5):553-60. 2002-11-01 [PMID: 12397014] (ICC, Human)	ICC	Human
Bagorda A, Guerra L, Di Sole F, Hemle-Kolb C, Cardone RA, Fanelli T, Reshkin SJ, Gisler SM, Murer H, Casavola V Reciprocal protein kinase A regulatory interactions between cystic fibrosis transmembrane conductance regulator and Na+/H+ exchanger isoform 3 in a renal polarized epithelial cell model. J. Biol. Chem., 2002-04-05;277(24):21480-8. 2002-04-05 [PMID: 11937500] (Western Blot, Amphibian)	Western Blot	Amphibian
Show All 76 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
	5 reviewed by: Verified Customer	WB	Mouse	02/19/2015	View Summary Application Western Blot Sample Tested See PMID 23060444 Species Mouse
	5 reviewed by: Verified Customer	IF	Other	02/19/2015	View Summary Application Immunofluorescence Sample Tested See PMID 20107177 Species Other
	4 reviewed by: Verified Customer	WB	Human	02/19/2015	View Summary Application Western Blot Sample Tested See PMID 21811577 Species Human
	4 reviewed by: Verified Customer	WB	Human	02/19/2015	View Summary Application Western Blot Sample Tested See PMID 22904170 Species Human
	4 reviewed by: Verified Customer	IP	Human	02/19/2015	View Summary Application Immunoprecipitation Sample Tested See PMID 21383017 Species Human
	4 reviewed by: Verified Customer	IHC-Fr	Mouse	02/19/2015	View Summary Application Immunohistochemistry-Frozen Sample Tested See PMID 23045527 Species Mouse
	4 reviewed by: Verified Customer	IF	Mouse	02/19/2015	View Summary Application Immunofluorescence Sample Tested See PMID 24204804 Species Mouse
	4 reviewed by: Verified Customer	IF	Mouse	02/19/2015	View Summary Application Immunofluorescence Sample Tested See PMID 22989883 Species Mouse
	4 reviewed by: Verified Customer	IF	Human	02/19/2015	View Summary Application Immunofluorescence Sample Tested See PMID 20351101 Species Human
	4 reviewed by: Verified Customer	Flow	Human	02/19/2015	View Summary Application Flow Cytometry Sample Tested See PMID 21561312 Species Human

Array MAB25031

• CFTR Antibodies
• CFTR ELISA Kit
• CFTR Proteins