HMBS Antibody

HMBS encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: IF/IHC.

Showing Publications 1 - 2 of 2.

Publications using NBP2-33600	Applications	Species
COrdoba KM, Serrano-Mendioroz I, JericO D et al. Recombinant porphobilinogen deaminase targeted to the liver corrects enzymopenia in a mouse model of acute intermittent porphyria Science translational medicine 2022-01-12 [PMID: 35020410] (IF/IHC)	IF/IHC
Jiang L, Berraondo P, Jerico D et al. Systemic messenger RNA as an etiological treatment for acute intermittent porphyria. Nat. Med. 2018-10-08 [PMID: 30297912] (IF/IHC, Mouse)	IF/IHC	Mouse

Array NBP2-33600

• HMBS Antibodies
• HMBS ELISA Kits
• HMBS Lysate
• HMBS Proteins