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HIST3H3 Antibody (2128A) [DyLight 755]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, Flow, ICC/IF
Clone
2128A
Clonality
Monoclonal
Host
Rabbit
Conjugate
DyLight 755

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC9448U-100UG
Alexa Fluor 405
IC9448V-100UG
Alexa Fluor 488
IC9448G-100UG
Alexa Fluor 532
FAB9448X
Alexa Fluor 594
IC9448T-100UG
Alexa Fluor 647
IC9448R-100UG
Alexa Fluor 700
IC9448N-100UG
Alexa Fluor 750
IC9448S-100UG
Allophycocyanin
FAB9448A
Biotin
FAB9448B
DyLight 350
FAB9448D
DyLight 405
FAB9448E
DyLight 488
FAB9448K
DyLight 550
FAB9448L
DyLight 594
FAB9448M
DyLight 650
FAB9448W
DyLight 680
FAB9448Y
FITC
FAB9448F
HRP
FAB9448H
Janelia Fluor 549
FAB9448I
Janelia Fluor 646
FAB9448J
PE
FAB9448P
PerCP
FAB9448C
Unconjugated
MAB9448-100
mFluor Violet 450 SE
FAB9448MFV450
mFluor Violet 500 SE
FAB9448MFV500
mFluor Violet 610 SE
FAB9448MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB9448-100
Carrier Free
MAB9448-100
Carrier Free
MAB9448-SP
Carrier Free
IC9448V-100UG
Carrier Free
IC9448T-100UG
Carrier Free
IC9448S-100UG
Carrier Free
IC9448R-100UG
Carrier Free
IC9448N-100UG
Carrier Free
IC9448G-100UG
Carrier Free
IC9448U-100UG
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HIST3H3 Antibody (2128A) [DyLight 755] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Human HIST3H3 synthetic peptide
Specificity
Detects human HIST3H3 in Western blots.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Immunocytochemistry
  • Immunohistochemistry
  • Intracellular Staining by Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for HIST3H3 Antibody (2128A) [DyLight 755]

  • H3 histone family, member T
  • H3.4
  • H3/G
  • H3/gH3.4
  • H3/T
  • H3FT
  • H3FTMGC126888
  • H3t
  • H3tMGC126886
  • HIST3H3
  • Histone 3, H3
  • histone cluster 3, H3
  • histone H3.1t

Background

Histones are nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber as they play a critical role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. The HIST3H3 gene is intronless and encodes a 136 amino acid long, 15 kDA histone H3.1t protein that lacks polyA tails and obtain a palindromic termination element. The HIST3H3 gene is located separately from the other H3 genes on the cluster on chromosome 6p22-p21.3. HIST3H3 participates in PKA signaling, development notch signaling pathway, histone modification, and interferon pathway through interactions with genes HIST1H4B, HIST4H4, HIST1H4A, HIST1H4C, and HIST1H4D. HIST3H3 has been researched regarding its role in immunodeficiency, leukemia, prostatitis, huntington's disease, lupus, multiple sclerosis, laryngeal cancer, and lymphomas.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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