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HES6 Antibody (OTI1D6) [FITC]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clone
OTI1D6
Clonality
Monoclonal
Host
Mouse
Conjugate
FITC

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-72008AF350
Alexa Fluor 405
NBP2-72008AF405
Alexa Fluor 488
NBP2-72008AF488
Alexa Fluor 532
NBP2-72008AF532
Alexa Fluor 594
NBP2-72008AF594
Alexa Fluor 647
NBP2-72008AF647
Alexa Fluor 700
NBP2-72008AF700
Alexa Fluor 750
NBP2-72008AF750
Allophycocyanin
NBP2-72008APC
Biotin
NBP2-72008B
CoraFluor 1
NBP2-72008CL1
DyLight 350
NBP2-72008UV
DyLight 405
NBP2-72008V
DyLight 488
NBP2-72008G
DyLight 550
NBP2-72008R
DyLight 594
NBP2-72008DL594
DyLight 650
NBP2-72008C
DyLight 680
NBP2-72008FR
DyLight 755
NBP2-72008IR
HRP
NBP2-72008H
Janelia Fluor 525
NBP2-72008JF525
Janelia Fluor 669
NBP2-72008JF669
PE
NBP2-72008PE
PerCP
NBP2-72008PCP
Unconjugated
NBP2-45971
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-45971
Azide and BSA Free
NBP2-72008
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HES6 Antibody (OTI1D6) [FITC] Summary

Immunogen
Full length human recombinant protein of human HES6 (NP_061115) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
HES6
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for HES6 Antibody (OTI1D6) [FITC]

  • BHLHB41
  • bHLHb41Class B basic helix-loop-helix protein 41
  • bHLHc23
  • C-HAIRY1
  • hairy and enhancer of split 6 (Drosophila)
  • Hairy and enhancer of split 6
  • HES-6
  • transcription cofactor HES-6

Background

HES6 is a transcription cofactor that itself does not bind to DNA but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. It also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCFEA2/E47, allowing ASCL1 and TCFEA2 to upregulate transcription in its presence. HES6 appears to have novel functions in tumor and cancer cell lines, although these have not yet been elucidated fully.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol HES6