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HDAC1 Antibody (S09-7G9)

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Western Blot: HDAC1 Antibody (S09-7G9) [NBP3-19652] - Western blot detection of HDAC1 in K562 cell lysates using NBP3-19652 (1:1000 diluted). Predicted band size: 55kDa. Observed band size: 62kDa.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clone
S09-7G9
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.3 mg/ml

Order Details

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HDAC1 Antibody (S09-7G9) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthetic peptide of human HDAC1 (Uniprot # Q13547)
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
HDAC1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1/2000
Theoretical MW
62 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
Preservative
0.01% Sodium Azide
Concentration
0.3 mg/ml
Purity
Affinity purified

Alternate Names for HDAC1 Antibody (S09-7G9)

  • EC 3.5.1.98
  • GON-10
  • HD1
  • HD1DKFZp686H12203
  • Histone Deacetylase 1
  • KDAC1
  • reduced potassium dependency, yeast homolog-like 1
  • RPD3L1
  • RPD3L1RPD3

Background

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for HDAC1 Antibody (NBP3-19652) (0)

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for HDAC1 Antibody (NBP3-19652) (0)

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Secondary Antibodies

 

Isotype Controls

Additional HDAC1 Products

Research Areas for HDAC1 Antibody (NBP3-19652)

Find related products by research area.

Blogs on HDAC1.

The role of DNMT3B in the co-incidence of methyltransferase and tumor suppressor expression in malignancies
Epigenetics is the process of heritable change in gene activity despite alteration of the hosts DNA sequence, essentially causing a change in a phenotype without a change in the genotype of a host. To change the gene sequence without interfering w...  Read full blog post.

The role of DNMT3A in development
Epigenetics is the study of heritable change in gene activity despite alteration of the hosts DNA sequence.  Change in gene activity done independently of the DNA sequence is achieved by way of histone and DNA methylation.  Gene silencing in DNA ...  Read full blog post.

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Bioinformatics

Gene Symbol HDAC1