Immunocytochemistry/ Immunofluorescence: GDF-6/BMP-13 Antibody [NBP1-91934] - Staining of human cell line LHCN-M2 shows localization to nucleoplasm, nuclear membrane & vesicles. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: GDF-6/BMP-13 Antibody [NBP1-91934] - Staining of human stomach, lower shows strong membranous and cytoplasmic positivity in glandular cells.
This antibody was developed against Recombinant Protein corresponding to amino acids: IYRTYSIAEKLGINASFFQSSKSANTITSFVDRGLDDLSHTPLRRQKYLFDVSMLSDKEELVGAELRLFRQAPSAPWGPPAGPLHVQLF
Predicted Species
Mouse (91%), Rat (91%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GDF6
Purity
Immunogen affinity purified
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for GDF-6/BMP-13 Antibody
BMP13
BMP-13
CDMP2
GDF16
GDF6
GDF-6
growth differentiation factor 6
Growth/differentiation factor 16
growth/differentiation factor 6
KFS
KFS1
KFSL
MCOP4
MCOPCB6
MGC158100
MGC158101
SCDO4
SGM1
Background
GDF6 encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily of secreted signaling molecules. It is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), which is a congenital disorder of spinal segmentation. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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