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GDF-1 Antibody [Unconjugated] - Propeptide

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

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GDF-1 Antibody [Unconjugated] - Propeptide Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse GDF-1 Propeptide
Pro25-Leu235
Accession # P20863
Specificity
Detects mouse GDF-1 Propeptide in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with mature recombinant mouse (rm) GDF-1 and rmGDF-3 Propeptide is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
GDF1
Purity Statement
Antigen Affinity-purified
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Applications/Dilutions

Dilutions
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for GDF-1 Antibody [Unconjugated] - Propeptide

  • DORV
  • DTGA3
  • embryonic growth/differentiation factor 1
  • GDF1
  • GDF-1
  • growth differentiation factor 1

Background

Mouse GDF-1 Propeptide is a 26 kDa, secreted monomeric glycopeptide. It is synthesized as part of a 357 amino acid (aa) preprocursor that contains a 23 aa signal sequence, a 214 aa Propeptide and a 120 aa mature molecule. Following secretion, the proregion is presumably proteolytically cleaved from the mature molecule at an Arg-Arg dibasic residue motif. The amino acid sequence of mouse GDF-1 Propeptide is 65% and 78% identical to that of human and rat GDF-1 Propeptide, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol GDF1
Uniprot