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GARS Antibody (OTI4G4) [DyLight 405]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clone
OTI4G4
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

Order Details

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GARS Antibody (OTI4G4) [DyLight 405] Summary

Immunogen
Full length recombinant protein of human GARS (NP_002038) produced in HEK293T cells.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
GARS
Purity
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for GARS Antibody (OTI4G4) [DyLight 405]

  • AP-4-A synthetase
  • Charcot-Marie-Tooth neuropathy 2D
  • Charcot-Marie-Tooth neuropathy, neuronal type, D
  • Diadenosine tetraphosphate synthetase
  • DSMAV
  • glycine tRNA ligase
  • Glycine--tRNA ligase
  • glycyl-tRNA synthetase
  • GlyRSEC 6.1.1.14
  • HMN5
  • SMAD1CMT2D

Background

GARS encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GARS