GAPDH-2 Antibody (2E3-2E10)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This gene encodes a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 10 of 12. Show All 12 Publications. Collapse Publications.

Publications using H00026330-M01	Applications	Species
Kim S, Hata A, Kang H. Down-Regulation of miR-96 by Bone Morphogenetic Protein Signaling is Critical for Vascular Smooth Muscle Cell Phenotype Modulation. J Cell Biochem. 2013-12-04 [PMID: 24375867]
Kang H, Louie J, Weisman A et al. Inhibition of microRNA-302 (miR-302) by bone morphogenetic protein 4 (BMP4) facilitates the BMP signaling pathway. J Biol Chem. 2012-09-17 [PMID: 22988237]
Kuravsky ML, Schmalhausen EV, Pozdnyakova NV, Muronetz VI. Isolation of antibodies against different protein conformations using immunoaffinity chromatography. Anal Biochem. 2012-04-03 [PMID: 22484035]
Kang H, Davis-Dusenbery BN, Nguyen PH et al. Bone morphogenetic protein 4 promotes vascular smooth muscle contractility by activating miR-21, which downregulates expression of the family of Dedicator of Cytokinesis (DOCK) proteins. J Biol Chem. 2011-12-09 [PMID: 22158624]
Davis-Dusenbery BN, Chan MC, Reno KE et al. Down-regulation of KLF4 by MIR-143/145 is critical for modulation of vascular smooth muscle cell phenotype by TGF-{beta} and BMP. J Biol Chem. 2011-06-13 [PMID: 21673106]
Chan MC, Weisman AS, Kang H et al. The amiloride derivative phenamil attenuates pulmonary vascular remodeling by activating NFAT and the BMP signaling pathway. Mol Cell Biol. 2010-12-06 [PMID: 21135135]
Elkina Y, Kuravsky M, Eldarov M et al. Recombinant human sperm-specific glyceraldehyde-3-phosphate dehydrogenase: Structural basis for enhanced stability. Biochim Biophys Acta. 2010-09-15 [PMID: 20833277]
Davis BN, Hilyard AC, Nguyen PH et al. Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha. Mol Cell. 2010-08-13 [PMID: 20705240]
Chan MC, Hilyard AC, Wu C et al. Molecular basis for antagonism between PDGF and the TGFbeta family of signalling pathways by control of miR-24 expression. EMBO J 29(3):559-73. 2010-02-03 [PMID: 20019669]
Davis BN, Hilyard AC, Nguyen PN et al. Induction of microrna-221 by platelet-derived growth factor signaling is critical for modulation of vascular smooth muscle phenotype. J Biol Chem. 2008-12-16 [PMID: 19088079]
Davis BN, Hilyard AC, Lagna G et al. SMAD proteins control DROSHA-mediated microRNA maturation. Nature;454(7200):56-61. 2008-07-03 [PMID: 18548003]
Shchutskaya YY, Elkina YL, Kuravsky ML et al. Investigation of glyceraldehyde-3-phosphate dehydrogenase from human sperms. Biochemistry (Mosc);73(2):185-91. 2008-02-01 [PMID: 18298375]
Show All 12 Publications. Collapse Publications.

Array H00026330-M01

• GAPDH-2 Antibodies
• GAPDH-2 Lysate
• GAPDH-2 Proteins