GAD2/GAD65 Antibody

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Mouse, Rat.

We have publications tested in 2 applications: ICC/IF, WB.

Showing Publications 1 - 3 of 3.

Publications using NBP1-33284	Applications	Species
Michalettos G, Walter HL, Antunes ARP Et al. Effect of Anti-inflammatory Treatment with AMD3100 and CX3CR1 Deficiency on GABAA Receptor Subunit and Expression of Glutamate Decarboxylase Isoforms After Stroke Molecular neurobiology 2021-08-20 [PMID: 34417725] (WB, Mouse)	WB	Mouse
Cai Y, Yang L, Hu G et al. Regulation of morphine-induced synaptic alterations: Role of oxidative stress, ER stress, and autophagy. J. Cell Biol. 2016-10-24 [PMID: 27810915] (WB, Rat)	WB	Rat
Grigoryan G, Segal M. Prenatal Stress Affects Network Properties of Rat Hippocampal Neurons Biol Psychiatry 2013-03-26 [PMID: 23541001] (ICC/IF, Rat)	ICC/IF	Rat

Images	Ratings	Applications	Species	Date	Details
	5 reviewed by: YONGJIE LAI	WB	Mouse	10/01/2014	View Summary Application Western Blot Sample Tested mouse brain lysate Species Mouse
	5 reviewed by: YONGJIE LAI	IF	Human	10/01/2014	View Summary Application Immunofluorescence Sample Tested pCMV-GAD65 plasmid transfected HEK293T cells Species Human

Array NBP1-33284

• GAD2/GAD65 Antibodies
• GAD2/GAD65 ELISA Kits
• GAD2/GAD65 Lysates
• GAD2/GAD65 Proteins