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G-CSFR/CD114 Antibody (723806) [CoraFluor™ 1]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
723806
Clonality
Monoclonal
Host
Rat
Conjugate
CoraFluor 1

Order Details

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G-CSFR/CD114 Antibody (723806) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse G-CSF R/CD114
Cys26-Asp626
Accession # P40223
Specificity
Detects mouse G-CSF R/CD114 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse (rm) GM-CSF R alpha, rmM-CSF R, recombinant human (rh) G-CSF R alpha, or rhGM-CSF R beta is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
Csf3r
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for G-CSFR/CD114 Antibody (723806) [CoraFluor™ 1]

  • CD114 antigen
  • CD114
  • colony stimulating factor 3 receptor (granulocyte)
  • CSF3R
  • Csfgr
  • G-CSF R
  • G-CSF receptor
  • GCSFR
  • G-CSFR
  • GCSFRG-CSF-R
  • granulocyte colony-stimulating factor receptor

Background

GCSF Receptor is encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variants encoding four different isoforms have been found for this gene, with three of the isoforms being membrane-bound and the other being secreted and soluble. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol Csf3r