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EZH1 Antibody

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Immunohistochemistry: EZH1 Antibody [NBP2-69048] - Immunohistochemical staining of human ovary shows moderate nuclear positivity in follicle cells.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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EZH1 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: YKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDRDTGNDWASSSSE
Predicted Species
Mouse (96%), Rat (92%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
EZH1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:2500 - 1:5000
  • Immunohistochemistry-Paraffin 1:2500 - 1:5000
Application Notes
Recommended conditions for IHC,Retrieval method: HIER pH6
Control Peptide
EZH1 Recombinant Protein Antigen (NBP2-69048PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for EZH1 Antibody

  • EC 2.1.1.356
  • EC 2.1.1.43
  • enhancer of zeste homolog 1 (Drosophila)
  • Enhancer of zeste homolog 1
  • ENX-2
  • EZH1
  • histone-lysine N-methyltransferase EZH1
  • KIAA0388
  • KIAA0388enhancer of zeste (Drosophila) homolog 1
  • KMT6B

Background

EZH1 is a human homolog of the Drosophila gene Enhancer of zeste E(z), a member of the polycomb group of transcriptional repressors. In mice, EZH1 is a regulator of homeotic gene expression implicated in the assembly of repressive protein complexes in chromatin. The strong sequence conservation between species suggests potential role for EZH1 in human development as a transcriptional regulator and as a component of protein complexes that stably maintain heterochromatin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Research Areas for EZH1 Antibody (NBP2-69048)

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Blogs on EZH1.

EZH1 has more to offer than gene repression
EZH1 is part of the Polycomb-group family of proteins, which are responsible for remodeling chromatin in genes and modulating epigenetic silencing during development.  Specifically, EZHI is a component of PRC2, or polycomb repressive complex-2.  PR...  Read full blog post.

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Bioinformatics

Gene Symbol EZH1