Home » ERR beta/NR3B2 » ERR beta Antibodies » ERR beta/NR3B2 Antibody - BSA Free

ERR beta/NR3B2 Antibody - BSA Free

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Immunohistochemistry-Paraffin: ERR beta/NR3B2 Antibody [NLS7131] - Colon, Carcinoma
Immunohistochemistry-Paraffin: ERR beta/NR3B2 Antibody [NLS7131] - Colon, Carcinoma
Immunohistochemistry-Paraffin: ERR beta/NR3B2 Antibody [NLS7131] - Human testis tissue after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: ERR beta/NR3B2 Antibody [NLS7131] - Analysis of anti-ESRRB / ERR Beta antibody with human lung, small cell carcinoma.
Immunohistochemistry-Paraffin: ERR beta/NR3B2 Antibody [NLS7131] - Prostate, Carcinoma

Product Details

Summary
Reactivity Hu, Mu, Po, Bv, Ca, Eq, Ha, Pm, Pm, Rb, Rt, Av, ChSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

Order Details

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ERR beta/NR3B2 Antibody - BSA Free Summary

Description
Product can be stored undiluted at 4C for up to 1 month.
Immunogen
Synthetic 15 amino acid peptide from ligand-binding domain of human ERR beta/NR3B2.
Epitope
Ligand-binding domain
Specificity
Human ESRRB. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ESRRG (67%).
Predicted Species
Rat (93%), Chicken (93%), Avian (93%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ESRRB
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 3 ug/ml
Application Notes
.
Publications
Read Publication using NLS7131.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 18472334). Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Bat (87%), Zebrafish (80%).

Packaging, Storage & Formulations

Storage
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ERR beta/NR3B2 Antibody - BSA Free

  • ERR beta
  • ERR2
  • ESRL2
  • ESRRB
  • estrogen-related receptor beta
  • NR3B2

Background

Estrogen-related receptor beta (ERR beta) a NR3 Steroid Receptor, has been shown to affect early placental development. ERR beta also can act as a repressor of transcriptional activity mediated by the glucocorticoid receptor (GR). ERR beta binds as a monomer to the extended half-site TNAAGTGCA and as a homodimer to the estrogen response element (ERE), palindromic thyroid hormone response element (TRE(pal)), and SF-1 response element, but not to the glucocorticoid response element (GRE). ERR beta mutations lead to abnormal development of the chorion and defective diploid trophoblast proliferation, and are lethal during midgestation. ERR beta expression has been documented in mice in the extraembryonic ectoderm that gives rise to the chorion. ESTs have been isolated from normal human eye, lung, and testis libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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ERR beta/NR3B2 Antibody - BSA Free
Species: Hu, Mu, Po, Bv, Ca, Eq, Ha, Pm, Pm, Rb, Rt, Av, Ch
Applications: IHC

Publications for ERR beta/NR3B2 Antibody (NLS7131)(1)

We have publications tested in 1 confirmed species: Mouse.


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Bioinformatics

Gene Symbol ESRRB
Entrez