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Endoglin/CD105 Antibody (MJ7/18) [PE]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IP
Clone
MJ7/18
Clonality
Monoclonal
Host
Rat
Conjugate
PE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-77666AF350
Alexa Fluor 405
NB100-77666AF405
Alexa Fluor 488
NB100-77666AF488
Alexa Fluor 532
NB100-77666AF532
Alexa Fluor 594
NB100-77666AF594
Alexa Fluor 647
NB100-77666AF647
Alexa Fluor 700
NB100-77666AF700
Alexa Fluor 750
NB100-77666AF750
Allophycocyanin
NB100-77666APC
Biotin
NB100-77666B
DyLight 350
NB100-77666UV
DyLight 405
NB100-77666V
DyLight 488
NB100-77666G-0.5ml
DyLight 550
NB100-77666R-0.5ml
DyLight 594
NB100-77666DL594
DyLight 650
NB100-77666C-0.5ml
DyLight 680
NB100-77666FR-500ul
DyLight 755
NB100-77666IR
FITC
NB100-77666F
HRP
NB100-77666H
Janelia Fluor 525
NB100-77666JF525
Janelia Fluor 549
NB100-77666JF549
Janelia Fluor 585
NB100-77666JF585
Janelia Fluor 635
NB100-77666JF635
Janelia Fluor 646
NB100-77666JF646
Janelia Fluor 669
NB100-77666JF669
PerCP
NB100-77666PCP
Unconjugated
NB100-77666
mFluor Violet 450 SE
NB100-77666MFV450
mFluor Violet 500 SE
NB100-77666MFV500
mFluor Violet 610 SE
NB100-77666MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB100-77666
Azide and BSA Free
NBP2-80718
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Endoglin/CD105 Antibody (MJ7/18) [PE] Summary

Immunogen
Inflamed mouse skin
Epitope
Endothelial cell selective TGB1 binding molecule-endoglin
Marker
Neo-endothelial Cells Marker
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
ENG
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow (Cell Surface)
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for Endoglin/CD105 Antibody (MJ7/18) [PE]

  • CD105 antigen
  • CD105
  • Endoglin
  • ENDOsler-Rendu-Weber syndrome 1
  • ENG
  • HHT1FLJ41744
  • ORW
  • ORW1

Background

CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and up-regulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF- szlig1, TGF- szlig3 and modulates TGF- szlig signaling by interacting with TGF- szlig receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2 and -7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging, prognosis, as well as has therapeutic potential for some solid tumors and other angiogenic diseases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Endoglin/CD105
Antibody (MJ7/18) [PE
NB100-77666PE
Endoglin/CD105 Antibody (MJ7/18) [PE]
Species: Mu
Applications: WB, Flow, ICC/IF, IHC, IP

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Endoglin/CD105 Antibody (NB100-77666PE). (Showing 1 - 2 of 2 FAQ).

  1. I wonder if you have a CD105 or CD34 antibody suitable for IHC that is specific for human and do not bind mouse?
    • We do not have any anti-human CD34 or CD105 antibodies that are confirmed to NOT detect the mouse protein. When we have tested an antibody and confirmed that it will not react with mouse samples, we will add Mu(-) to the datasheet, and unfortunately all of our CD105 and CD34 antibodies will either detect the mouse protein, or they have not been used in mouse samples before.
  2. We are interested in CD105 antibodies that could react with dog, please let me know which products in your catalog you would recommend.
    • We do not currently carry any CD105 antibodies that have been validated for use in dog samples. However, if you are interested in testing any of our CD105 antibodies with dog samples you would be eligible for our Innovators Reward Program, in which you can get a discount voucher for the purchase price of the product. Please contact us at innovators@novusbio.com with any questions regarding this program.

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ENG