EMP/MAEA Antibody

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

EMP (erythroblast macrophage protein), also called MAEA (macrophage-erythroblast attacher), is a 36-45 kDa membrane-associated protein in macrophages and erythroblasts within erythroblastic islands. EMP is essential to the process of nuclear extrusion in the transition of erythroblasts to reticulocytes. Within the region used as an immunogen, human EMP shares 98% amino acid (aa) sequence identity with mouse and rat EMP. Four potential isoforms of the canonical 396 aa form encode 360, 355, 328 and 245 aa, with insertions and deletions occurring after aa 150.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: Immunoprecipitation, Western Blot.

Showing Publications 1 - 7 of 7.

Publications using AF7288	Applications	Species
Simwela, NV;Johnston, L;Pavinski Bitar, P;Jaecklein, E;Altier, C;Sassetti, CM;Russell, DG; Genome-wide screen of Mycobacterium tuberculosis- infected macrophages identified the GID/CTLH complex as a determinant of intracellular bacterial growth bioRxiv : the preprint server for biology 2024-05-08 [PMID: 38766174] (Western Blot, Mouse)	Western Blot	Mouse
Wang, Y;Guo, R;Piedras, BI;Tang, HY;Asara, JM;Tempera, I;Lieberman, PM;Gewurz, BE; The CTLH Ubiquitin Ligase Substrates ZMYND19 and MKLN1 Negatively Regulate mTORC1 at the Lysosomal Membrane Research square 2024-04-24 [PMID: 38746323] (Western Blot, Human)	Western Blot	Human
Weaam I Mohamed, Sophia L Park, Julius Rabl, Alexander Leitner, Daniel Boehringer, Matthias Peter The human GID complex engages two independent modules for substrate recruitment EMBO reports 11/4/2021 [PMID: 34647674]
Sherpa D, Chrustowicz J, Qiao S et al. GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme Molecular cell 4/22/2021 [PMID: 33905682]
SHA Soliman, AE Stark, ML Gardner, SW Harshman, CC Breece, F Amari, A Orlacchio, M Chen, A Tessari, JA Martin, R Visone, MA Freitas, KMD La Perle, D Palmieri, V Coppola Tagging enhances histochemical and biochemical detection of Ran Binding Protein 9 in vivo and reveals its interaction with Nucleolin Sci Rep, 2020-04-28;10(1):7138. 2020-04-28 [PMID: 32346083] (Immunoprecipitation, Mouse)	Immunoprecipitation	Mouse
MER Maitland, G Onea, CA Chiasson, X Wang, J Ma, SE Moor, KR Barber, GA Lajoie, GS Shaw, C Schild-Pou The mammalian CTLH complex is an E3 ubiquitin ligase that targets its subunit muskelin for degradation Sci Rep, 2019-07-08;9(1):9864. 2019-07-08 [PMID: 31285494] (Western Blot, Human)	Western Blot	Human
F Lampert, D Stafa, A Goga, MV Soste, S Gilberto, N Olieric, P Picotti, M Stoffel, M Peter The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation Elife, 2018-06-18;7(0):. 6/18/2018 [PMID: 29911972]

Array AF7288

• EMP/MAEA Antibodies
• EMP/MAEA Lysate
• EMP/MAEA Proteins