eIF4E Antibody

eIF4E is a protein that modulates the translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. . Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.

Showing Publications 1 - 2 of 2.

Publications using NB100-58833	Applications	Species
Smith EM, Benbahouche NEH, Morris K et al. The mTOR regulated RNA-binding protein LARP1 requires PABPC1 for guided mRNA interaction Nucleic acids research 2020-12-17 [PMID: 33332560] (WB, Human) Details: HeLa	WB	Human
Dong Z, Chen W, Chen C et al. CUL3 Deficiency Causes Social Deficits and Anxiety-like Behaviors by Impairing Excitation-Inhibition Balance through the Promotion of Cap-Dependent Translation Neuron 2019-11-21 [PMID: 31780330]

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Wei-Ting Lu	WB	Other	02/04/2012	View Summary Application Western Blot Sample Tested HeLa whole cell lysate, Sample Amount: 25 ug Species Other Lot a1

Array NB100-58833

• eIF4E Antibodies
• eIF4E Lysate
• eIF4E Proteins