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DAB2IP Antibody

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Biological Strategies: Western Blot: DAB2IP Antibody [NBP1-30081] - Detection of Mouse DAB2IP by Western Blot. Samples: Whole cell lysate (50 ug) from TCMK-1, Renca, 4T1, and CT26.WT cells. Antibodies: Affinity ...read more
Independent Antibodies: Western Blot: DAB2IP Antibody [NBP1-30081] - Whole cell lysate from HeLa cells. DAB2IP was also IPed by rabbit anti-DAB2IP antibody NBP1-30082. For blotting immunoprecipitated DAB2IP, the ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml

Order Details

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DAB2IP Antibody Summary

Immunogen
Antigen maps to a region between residue 850 and 900 of human disabled homolog 2 interacting protein using the numbering given in entry CAQ10385.1
Predicted Species
Rat (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DAB2IP
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunoprecipitation 2-5 ug/mg lysate
  • Western Blot 1:2000-1:10000
Theoretical MW
132 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using NBP1-30081.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for DAB2IP Antibody

  • AIP1FLJ39072
  • ASK-interacting protein 1
  • DAB2 interacting protein
  • DAB2 interaction protein
  • DAB2-interacting protein
  • DIP1/2
  • disabled homolog 2-interacting protein
  • DOC-2/DAB2 interactive protein
  • KIAA1743AF9Q34ASK1-interacting protein 1
  • nGAP-like protein

Background

DAB2-interacting protein (DAB2IP) functions as a Ras GTPase-activating protein. Through its interaction with MAP3K5, it disrupts the association of MAP3K5 with the inhibitory 14-3-3 complex. DAB2IP also Mediates TNF/TRAF2-induced MAP3K5-JNK activation, while it inhibits CHUK-NF-kappa-B signaling. DAB2IP may act as a tumor suppressor gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for DAB2IP Antibody (NBP1-30081)(1)

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for DAB2IP Antibody (NBP1-30081) (0)

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Secondary Antibodies

 

Isotype Controls

Additional DAB2IP Products

Array NBP1-30081

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Bioinformatics

Gene Symbol DAB2IP
Entrez
Uniprot