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csl/RBPJK Antibody (S05-6G4)

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Western Blot: csl/RBPJK Antibody (S05-6G4) [NBP3-19759] - Western blot detection of csl/RBPJK in Rat Brain, C6 cell lysates using NBP3-19759 (1:1000 diluted). Predicted band size: 56kDa. Observed band size: 61kDa.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clone
S05-6G4
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.3 mg/ml

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csl/RBPJK Antibody (S05-6G4) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthetic peptide of human csl/RBPJK (Uniprot # Q06330)
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
RBPJ
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1/1000-1/5000
Theoretical MW
61 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
Preservative
0.01% Sodium Azide
Concentration
0.3 mg/ml
Purity
Affinity purified

Alternate Names for csl/RBPJK Antibody (S05-6G4)

  • CBF1
  • CBF-1
  • CSL
  • H-2K binding factor-2
  • IGKJRB1
  • IGKJRB1RBPSUHCBF1
  • IGKJRBRBP-J kappa
  • immunoglobulin kappa J region recombination signal binding protein 1
  • J kappa-recombination signal-binding protein
  • KBF2
  • RBPJ
  • RBP-JK
  • RBPJKMGC61669
  • RBP-Jrecombining binding protein suppressor of hairless (Drosophila)
  • RBPSUH
  • recombination signal binding protein for immunoglobulin kappa J region
  • recombining binding protein suppressor of hairless
  • Renal carcinoma antigen NY-REN-30
  • SUH
  • suppressor of hairless homolog

Background

Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol RBPJ