PDLIM7 Antibody

PDLIM7 is encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: ICC/IF, WB.

Showing Publications 1 - 3 of 3.

Publications using NBP1-84841	Applications	Species
Healy MD, Sacharz J, McNally KE et al. Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins Structure (London, England : 1993) 2022-10-18 [PMID: 36302387] (ICC/IF, Human)	ICC/IF	Human
Elbediwy A, Vanyai H, Diaz-de-la-Loza MD et al. Enigma proteins regulate YAP mechanotransduction J. Cell. Sci. 2018-11-22 [PMID: 30404826] (WB, Human)	WB	Human
Li A, Ponten F, dos Remedios CG. The interactome of LIM domain proteins: the contributions of LIM domain proteins to heart failure and heart development. Proteomics 2012-01-01 [PMID: 22253135]

Array NBP1-84841

• PDLIM7 Antibodies
• PDLIM7 Lysate
• PDLIM7 Proteins