csl/RBPJK Products

Description

Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence

Bioinformatics

Entrez	3516 Human
Uniprot	NM_005349 Human NM_203284 Human NP_056958.3 Human NP_976028 Human NP_976029 Human Q06330 Human
Product By Gene ID	3516
Alternate Names	CBF-1 csl H-2K binding factor-2 IGKJRB1RBPSUHCBF1 IGKJRBRBP-J kappa immunoglobulin kappa J region recombination signal binding protein 1 J kappa-recombination signal-binding protein KBF2 RBP-JK RBPJKMGC61669 RBP-Jrecombining binding protein suppressor of hairless (Drosophila) recombination signal binding protein for immunoglobulin kappa J region recombining binding protein suppressor of hairless Renal carcinoma antigen NY-REN-30 SUH suppressor of hairless homolog