CD3 epsilon Antibody (UCHT1) [Allophycocyanin]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

CD3 epsilon is a key signaling molecule that participates in the formation of the T Cell Receptor (TCR). The alpha beta TCR is composed of six distinct subunits. There is an alpha -beta disulfide-linked heterodimer that recognizes antigen, and this is accompanied by four CD3 subunits that transduce an intracellular signal. CD3 epsilon forms a heterodimer with both CD3 gamma and CD3δ, creating two signaling complexes. These two heterodimers are supplemented by a CD3 zeta zeta homodimer that lies in the center of the TCR complex, generating a fully-functional TCR (2). 

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: Bioassay, Flow Cytometry.

Showing Publications 1 - 6 of 6.

Publications using FAB100A	Applications	Species
Luca Tirinato, Francesca Pagliari, Simone Di Franco, Elisa Sogne, Maria Grazia Marafioti, Jeanette Jansen et al. ROS and Lipid Droplet accumulation induced by high glucose exposure in healthy colon and Colorectal Cancer Stem Cells Genes & Diseases 2020-12-01 [PMID: 33335962]
Kellie N Smith Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells MBio, 2016-05-31;7(3):. 2016-05-31 [PMID: 27247230]
Hagen J, Zimmerman R, Goetz C, Bonnevier J, Houchins J, Reagan K, Kalyuzhny A Comparative Multi-Donor Study of IFNgamma Secretion and Expression by Human PBMCs Using ELISPOT Side-by-Side with ELISA and Flow Cytometry Assays. Cells, 2015-02-11;4(1):84-95. 2015-02-11 [PMID: 25679284] (Bioassay, Human)	Bioassay	Human
Prendergast A, Prado JG, Kang YH, Chen F, Riddell LA, Luzzi G, Goulder P, Klenerman P HIV-1 infection is characterized by profound depletion of CD161+ Th17 cells and gradual decline in regulatory T cells. AIDS, 2010-02-20;24(4):491-502. 2010-02-20 [PMID: 20071976] (Flow Cytometry, Human)	Flow Cytometry	Human
Kirwan M, Beswick R, Vulliamy T, Nathwani AC, Walne AJ, Casimir C, Dokal I Exogenous TERC alone can enhance proliferative potential, telomerase activity and telomere length in lymphocytes from dyskeratosis congenita patients. Br. J. Haematol., 2008-11-20;144(5):771-81. 2008-11-20 [PMID: 19036115] (Flow Cytometry, Human)	Flow Cytometry	Human
Garcia G, Humbert M, Capel F, Rimaniol AC, Escourrou P, Emilie D, Godot V Chemokine receptor expression on allergen-specific T cells in asthma and allergic bronchopulmonary aspergillosis. Allergy, 2007-02-01;62(2):170-7. 2007-02-01 [PMID: 17298426] (Flow Cytometry, Human)	Flow Cytometry	Human

Array FAB100A

• CD3 epsilon Antibodies
• CD3 epsilon ELISA Kit
• CD3 epsilon Lysate
• CD3 epsilon Proteins
• CD3 epsilon Proteins and Enzyme