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Human CD21 ELISA Kit (Colorimetric)

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ELISA: Human CD21 ELISA Kit (Colorimetric) [NBP3-14628] - Example of Human CD21 Standard Curve.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Suitable Sample Type
Serum, Plasma, Cell culture supernatant
Standard Curve Range
3.12-100 U/ml
Sensitivity
3 U/ml

Order Details

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Human CD21 ELISA Kit (Colorimetric) Summary

Description
Incubation: 1 hours 45 minutes
Specificity
Recognizes human soluble CD21
Standard Curve Range
3.12-100 U/ml
Sensitivity
3 U/ml
Assay Type
Sandwich ELISA
Inter-Assay
CV% < 5.2
Intra-Assay
CV% < 4.45
Sample Volume
100 ul
Kit Type
ELISA Kit (Colorimetric)
Gene
CR2

Applications/Dilutions

Dilutions
  • ELISA

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.

Kit Components

Components
  1. Biotinylated secondary antibody
  2. Buffers
  3. Controls (where applicable)
  4. Detailed procedure.
  5. Pre-coated strip plates
  6. Standards
  7. Stop reagents
  8. Streptavidin-HRP
  9. TMB

Alternate Names for Human CD21 ELISA Kit (Colorimetric)

  • C3DR
  • C3DRSLEB9
  • CD21 antigen
  • CD21
  • Complement C3d receptor
  • complement component (3d/Epstein Barr virus) receptor 2
  • complement receptor type 2
  • CR2
  • EBV receptor
  • Epstein-Barr virus receptor

Background

CD21 (complement receptor 2, CR2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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CD19: An Undoubted Biomarker for B Cells
CD19 is a cell surface protein member of the large immunoglobulin superfamily that complexes with CD21, CD81, and CD225 in the membrane of mature B-cells. A major function of CD19 is to assemble with the antigen receptor of B-lymphocytes to decrease t...  Read full blog post.

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Bioinformatics

Gene Symbol CR2