Human CD21 ELISA Kit (Colorimetric) Summary
Description |
Incubation: 1 hours 45 minutes |
Specificity |
Recognizes human soluble CD21 |
Standard Curve Range |
3.12-100 U/ml |
Sensitivity |
3 U/ml |
Assay Type |
Sandwich ELISA |
Inter-Assay |
CV% < 5.2 |
Intra-Assay |
CV% < 4.45 |
Sample Volume |
100 ul |
Kit Type |
ELISA Kit (Colorimetric) |
Gene |
CR2 |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Store at 4C. Do not freeze. |
Kit Components
Components
|
- Biotinylated secondary antibody
- Buffers
- Controls (where applicable)
- Detailed procedure.
- Pre-coated strip plates
- Standards
- Stop reagents
- Streptavidin-HRP
- TMB
|
Alternate Names for Human CD21 ELISA Kit (Colorimetric)
Background
CD21 (complement receptor 2, CR2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are
guaranteed for 6 months from date of receipt.
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