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CD21 Antibody (544408) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clone
544408
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB4909U-100UG
Alexa Fluor 405
FAB4909V-100UG
Alexa Fluor 488
FAB4909G-100UG
Alexa Fluor 532
FAB4909X
Alexa Fluor 594
FAB4909T-100UG
Alexa Fluor 647
FAB4909R-100UG
Alexa Fluor 700
FAB4909N-100UG
Alexa Fluor 750
FAB4909S-100UG
Allophycocyanin/Cy7
FAB4909APCCY7
Biotin
FAB4909B
CoraFluor 1
FAB4909CL1
DyLight 350
FAB4909D
DyLight 405
FAB4909E
DyLight 488
FAB4909K
DyLight 550
FAB4909L
DyLight 594
FAB4909M
DyLight 650
FAB4909W
DyLight 680
FAB4909Y
DyLight 755
FAB4909Z
HRP
FAB4909H
Janelia Fluor 525
FAB4909JF525
Janelia Fluor 549
FAB4909I
Janelia Fluor 669
FAB4909JF669
PE/Atto594
FAB4909PEATT594
PE/Cy5.5
FAB4909PECY55
PE/Cy7
FAB4909PECY7
PerCP
FAB4909C
Unconjugated
MAB4909
mFluor Violet 450 SE
FAB4909MFV450
mFluor Violet 500 SE
FAB4909MFV500
mFluor Violet 610 SE
FAB4909MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB4909
Carrier Free
MAB4909
Carrier Free
MAB4909-SP
Carrier Free
FAB4909V-100UG
Carrier Free
FAB4909U-100UG
Carrier Free
FAB4909T-100UG
Carrier Free
FAB4909S-100UG
Carrier Free
FAB4909R-100UG
Carrier Free
FAB4909N-100UG
Carrier Free
FAB4909G-100UG
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CD21 Antibody (544408) [Janelia Fluor® 646] Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human CD21
Ile21-Arg971
Accession # P20023
Specificity
Detects human CD21 in direct ELISAs and Western blots.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CR2
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for CD21 Antibody (544408) [Janelia Fluor® 646]

  • C3DR
  • C3DRSLEB9
  • CD21 antigen
  • CD21
  • Complement C3d receptor
  • complement component (3d/Epstein Barr virus) receptor 2
  • complement receptor type 2
  • CR2
  • EBV receptor
  • Epstein-Barr virus receptor

Background

CD21 (complement receptor 2, CR2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CR2