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CCR2 Antibody (890231R) [Janelia Fluor® 585]

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Product Details

Summary
Reactivity RtSpecies Glossary
Applications Flow, CyTOF-ready
Clone
890231R
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 585

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB8368RU-100UG
Alexa Fluor 405
FAB8368RV-100UG
Alexa Fluor 488
FAB8368RG-100UG
Alexa Fluor 532
FAB8368RX
Alexa Fluor 594
FAB8368RT-100UG
Alexa Fluor 647
FAB8368RR-100UG
Alexa Fluor 700
FAB8368RN-100UG
Alexa Fluor 750
FAB8368RS-100UG
Allophycocyanin
FAB8368RA
Allophycocyanin/Cy7
FAB8368RAPCCY7
Biotin
FAB8368RB
CoraFluor 1
FAB8368RCL1
DyLight 350
FAB8368RD
DyLight 405
FAB8368RE
DyLight 488
FAB8368RK
DyLight 550
FAB8368RL
DyLight 594
FAB8368RM
DyLight 650
FAB8368RW
DyLight 680
FAB8368RY
DyLight 755
FAB8368RZ
FITC
FAB8368RF
HRP
FAB8368RH
Janelia Fluor 525
FAB8368RJF525
Janelia Fluor 549
FAB8368RI
Janelia Fluor 635
FAB8368RJF635
Janelia Fluor 646
FAB8368RJ
Janelia Fluor 669
FAB8368RJF669
PE
FAB8368RP
PE/Atto594
FAB8368RPEATT594
PE/Cy5.5
FAB8368RPECY55
PE/Cy7
FAB8368RPECY7
PerCP
FAB8368RC
Unconjugated
MAB8368R-100
mFluor Violet 450 SE
FAB8368RMFV450
mFluor Violet 500 SE
FAB8368RMFV500
mFluor Violet 610 SE
FAB8368RMFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB8368R-100
Carrier Free
MAB8368R-100
Carrier Free
MAB8368R-SP
Carrier Free
FAB8368RN-100UG
Carrier Free
FAB8368RV-100UG
Carrier Free
FAB8368RU-100UG
Carrier Free
FAB8368RT-100UG
Carrier Free
FAB8368RS-100UG
Carrier Free
FAB8368RR-100UG
Carrier Free
FAB8368RG-100UG
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CCR2 Antibody (890231R) [Janelia Fluor® 585] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
NS0 mouse myeloma cell line transfected with rat CCR2
Accession # O55193
Specificity
Detects rat CCR2 in direct ELISAs.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Innovator's Reward
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for CCR2 Antibody (890231R) [Janelia Fluor® 585]

  • C-C chemokine receptor type 2
  • C-C CKR-2
  • CC-CKR-2
  • CC-CKR-2CKR2B
  • CCR2
  • CCR-2
  • CCR2A
  • CCR2B
  • CD192 antigen
  • CD192
  • chemokine (C-C motif) receptor 2
  • CKR2
  • CKR2A
  • CMKBR2
  • CMKBR2MGC111760
  • FLJ78302
  • MCP-1 receptor
  • MCP-1-R
  • MCP-1-RMGC103828
  • MGC168006
  • Monocyte chemoattractant protein 1 receptor
  • monocyte chemotactic protein 1 receptor

Background

CCR2, or C C chemokine receptor type 2, is a receptor for several monocyte chemo attractant proteins (MCP1, MCP3, MCP4) which specifically mediate monocyte chemotaxis. CCR2 transduces such signals by increasing the intracellular level of calcium ions. For example, MCP1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. CCR2 is also an alternative coreceptor with CD4 for HIV1 infection. CCR2 has two isoforms and has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen and thymus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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