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CCR2 Antibody (48607R) [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
48607R
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB150RU-100UG
Alexa Fluor 405
FAB150RV-100UG
Alexa Fluor 488
FAB150RG-100UG
Alexa Fluor 532
FAB150RX
Alexa Fluor 594
FAB150RT-100UG
Alexa Fluor 647
FAB150RR-100UG
Alexa Fluor 700
FAB150RN-100UG
Alexa Fluor 750
FAB150RS-100UG
Allophycocyanin
FAB150RA
Allophycocyanin/Cy7
FAB150RAPCCY7
Biotin
FAB150RB
CoraFluor 1
FAB150RCL1
DyLight 350
FAB150RD
DyLight 488
FAB150RK
DyLight 550
FAB150RL
DyLight 594
FAB150RM
DyLight 650
FAB150RW
DyLight 680
FAB150RY
DyLight 755
FAB150RZ
FITC
FAB150RF
HRP
FAB150RH
Janelia Fluor 525
FAB150RJF525
Janelia Fluor 549
FAB150RI
Janelia Fluor 585
FAB150RJF585
Janelia Fluor 635
FAB150RJF635
Janelia Fluor 646
FAB150RJ
Janelia Fluor 669
FAB150RJF669
PE
FAB150RP
PE/Atto594
FAB150RPEATT594
PE/Cy5.5
FAB150RPECY55
PE/Cy7
FAB150RPECY7
PerCP
FAB150RC
Unconjugated
MAB150R-100
mFluor Violet 450 SE
FAB150RMFV450
mFluor Violet 500 SE
FAB150RMFV500
mFluor Violet 610 SE
FAB150RMFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB150R-100
Carrier Free
MAB150R-100
Carrier Free
MAB150R-SP
Carrier Free
FAB150RV-100UG
Carrier Free
FAB150RU-100UG
Carrier Free
FAB150RT-100UG
Carrier Free
FAB150RS-100UG
Carrier Free
FAB150RR-100UG
Carrier Free
FAB150RG-100UG
Carrier Free
FAB150RN-100UG
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CCR2 Antibody (48607R) [DyLight 405] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human CCR2
Met1-Leu360
Accession # NP_001116868
Specificity
Detects human CCR2 in direct ELISAs.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Purity
Protein A or G purified from cell culture supernatant
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from cell culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CCR2 Antibody (48607R) [DyLight 405]

  • C-C chemokine receptor type 2
  • C-C CKR-2
  • CC-CKR-2
  • CC-CKR-2CKR2B
  • CCR2
  • CCR-2
  • CCR2A
  • CCR2B
  • CD192 antigen
  • CD192
  • chemokine (C-C motif) receptor 2
  • CKR2
  • CKR2A
  • CMKBR2
  • CMKBR2MGC111760
  • FLJ78302
  • MCP-1 receptor
  • MCP-1-R
  • MCP-1-RMGC103828
  • MGC168006
  • Monocyte chemoattractant protein 1 receptor
  • monocyte chemotactic protein 1 receptor

Background

CCR2, or C C chemokine receptor type 2, is a receptor for several monocyte chemo attractant proteins (MCP1, MCP3, MCP4) which specifically mediate monocyte chemotaxis. CCR2 transduces such signals by increasing the intracellular level of calcium ions. For example, MCP1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. CCR2 is also an alternative coreceptor with CD4 for HIV1 infection. CCR2 has two isoforms and has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen and thymus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Isotype Controls

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