Independent Antibodies: Western Blot: BRM Antibody [NB100-55308] - Detection of human SMARCA2/BRM by western blot and immunoprecipitation. Samples: Whole cell lysate (5, 15 and 50 ug for WB; 1 mg for IP, 20% of ...read more
The immunogen recognized by this antibody maps to a region between residue 100 and 150 of human SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 using the numbering given in entry CAA51407.1 (GeneID 6595).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SMARCA2
Purity
Immunogen affinity purified
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global transcription activator homologous sequence
hBRM
hBRMMGC74511
hSNF2a
probable global transcription activator SNF2L2
Protein brahma homolog
SMARCA2
SNF2
SNF2/SWI2-like protein 2
SNF2A
SNF2-alpha
SNF2L2
SNF2L2BAF190
SNF2LA
SNF2-like 2
Sth1p
subfamily a, member 2
sucrose nonfermenting 2-like protein 2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily A member 2
SWI2
Background
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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