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BRIC Antibody

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Orthogonal Strategies: Immunohistochemistry-Paraffin: BRIC Antibody [NBP1-90068] - Staining in human rectum and lymph node tissues using anti-ATP8B1 antibody. Corresponding ATP8B1 RNA-seq data are presented for ...read more
Independent Antibodies: Immunohistochemistry-Paraffin: BRIC Antibody [NBP1-90068] - Staining of human cerebral cortex, kidney, liver and lymph node using Anti-ATP8B1 antibody NBP1-90068 (A) shows similar protein ...read more
Immunohistochemistry-Paraffin: BRIC Antibody [NBP1-90068] - Staining of human kidney.
Immunohistochemistry-Paraffin: BRIC Antibody [NBP1-90068] - Staining of human lymph node shows low expression as expected.
Immunohistochemistry-Paraffin: BRIC Antibody [NBP1-90068] - Staining of human rectum shows high expression.
Immunohistochemistry-Paraffin: BRIC Antibody [NBP1-90068] - Staining of human cerebral cortex.
Immunohistochemistry-Paraffin: BRIC Antibody [NBP1-90068] - Staining of human liver.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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BRIC Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: TTFDEDSQPNDEVVPYSDDETEDELDDQGSAVEPEQNRVNREAEENREPFRKECTWQVKANDRKYHEQPHFMNTKFLCIKESKYANNAIKTYKYNAFTFIPMNLFEQF
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ATP8B1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
BRIC Protein (NBP1-90068PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%), Rat (88%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for BRIC Antibody

  • ATPase class I type 8B member 1
  • ATPase, aminophospholipid transporter, class I, type 8B, member 1
  • ATPase, class I, type 8B, member 1
  • ATPICPFIC1
  • BRIC
  • EC 3.6.3
  • EC 3.6.3.1
  • Familial intrahepatic cholestasis type 1
  • FIC1phospholipid-transporting ATPase IC
  • PFICE1-E2 ATPase
  • probable phospholipid-transporting ATPase IC

Background

BRIC encodes a member of the P-type cation transport ATPase family, which belongs to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. Mutations in this gene may result in progressive familial intrahepatic cholestasis type 1 and in benign recurrent intrahepatic cholestasis. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ATP8B1