GGT1 Antibody (1F9)

This product is produced by and distributed for Abnova, a company based in Taiwan.

Human gamma-glutamyltransferase catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. This heteroduplex enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein, and is present in tissues involved in absorption and secretion. This enzyme is a member of the gamma-glutamyltransferase protein family, of which many members have not yet been fully characterized. This gene encodes several transcript variants; studies suggest that many transcripts of this gene family may be non-functional or represent pseudogenes. The functional transcripts which have been fully characterized have been grouped and classified as type I gamma-glutamyltransferase. Complex splicing events may take place in a tissue-specific manner, resulting in marked dissimilarity in the 5' UTRs. Several 5' UTR transcript variants of the type I gene have been identified in different tissues and cancer cells.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IF/IHC.

Showing Publications 1 - 10 of 10.

Publications using H00002678-M01	Applications	Species
Daisuke Y, Mako K, Shun K et al. Rapid imaging of thymoma and thymic carcinoma with a fluorogenic probe targeting ?-glutamyltranspeptidase. Sci Rep. 2023-03-07 [PMID: 36882498]
Shun K, Takafusa Y, Haruaki H et al. r-Glutamyl Hydroxymethyl Rhodamine Green Fluorescence as a Prognostic Indicator for Lung Cancer. Gen Thorac Cardiovasc Surg. 2020-06-02 [PMID: 32488832]
Akashi T, Isomoto H, Matsushima K et al. A novel method for rapid detection of a Helicobacter pylori infection using a ?-glutamyltranspeptidase-activatable fluorescent probe. Sci Rep. 2019-07-01 [PMID: 31263136]
Kubo H, Hanaoka K, Kuriki Y et al. Rapid detection of metastatic lymph nodes of colorectal cancer with a gamma-glutamyl transpeptidase-activatable fluorescence probe. Sci Rep 2018-12-12 [PMID: 30542087]
Grammatikopoulos T, Deheragoda M, Strautnieks S et al. Reduced Hepatocellular Expression of Canalicular Transport Proteins in Infants with Neonatal Cholestasis and Congenital Hypopituitarism J. Pediatr. 2018-06-20 [PMID: 29935878] (IF/IHC, Human)	IF/IHC	Human
Kawakami K, Fujita Y, Matsuda Y et al. Gamma-glutamyltransferase activity in exosomes as a potential marker for prostate cancer. BMC Cancer 2017-05-05 [PMID: 28476099]
Blackmore L, Knisely AS, Hartley JL et al. Polymorphisms in ABCB11 and ATP8B1 Associated with Development of Severe Intrahepatic Cholestasis in Hodgkin's Lymphoma. Journal of Clinical and Experimental Hepatology. 2012-01-01 [PMID: 25755490]
Grau L, Luque-Garcia JL, Gonzalez-Peramato P et al. A quantitative proteomic analysis uncovers the relevance of CUL3 in bladder cancer aggressiveness. PLoS One. 2013-01-01 [PMID: 23308193] (Human)		Human
West MB, Wickham S, Quinalty LM et al. Autocatalytic cleavage of human {gamma}-glutamyl transpeptidase is highly dependent on N-glycosylation at asparagine 95. J Biol Chem. 2011-06-28 [PMID: 21712391]
West MB, Segu ZM, Feasley CL et al. Analysis of site-specific glycosylation of renal and hepatic gamma-glutamyl transpeptidase from normal human tissue. J Biol Chem. 2010-07-09 [PMID: 20622017]

Array H00002678-M01

• GGT1 Antibodies
• GGT1 ELISA Kits
• GGT1 Lysates
• GGT1 Proteins and Enzyme